Prenatal development (ch 4) Flashcards
Germinal Period
First stage of prenatal dev.
- lasts approximately two weeks –
- zygote divides through mitosis and forms blastocyst that implants into blood vessels of uterine wall
- Only half of fertilized ova implant successfully
- 15-20 percent recognized pregnancies miscarry
- 50 percent of unrecognized pregnancies miscarry
Day 1 of Germinal period
Fertilization usually occurs within 24 hours of ovulation
Day 2 of Germinal period
The single-celled zygote begins to divide 24-36 hours after fertilization
Day 3-4 of Germinal period
- The mass has 16 cells – called morula
- Travelling down fallopian tube to the uterus
Day 5 of Germinal period
- Inner cell mass forms – entire mass called Blastocyst
- Size of pinhead
Day 6-7 of Germinal period
Blastocyst attaches to the wall of the uterus
Day 8-14 of Germinal period
Blastocyst becomes fully embedded in the wall of the uterus
- Now have approximately 250 cells
Embryonic period
- week 3-8
- Organogenesis - formation of every major organ
- Layers of blastocyst differentiate forming structures that sustain development
- Sexual differentiation
Events of embryonic period - Wk 3
- Embryo 1/10 of an inch
- Become elongated
- Three layers emerge: ectoderm, mesoderm, and endoderm
Embryonic period Week 4:
- Embryo so curved that the two ends almost touch
- Outer layer (ectoderm) folds into the neural tube
- From mesoderm, a tiny heart forms and begins to beat
- Endoderm differentiates into gastrointestinal tract and lungs
- 21-28 days: eyes develop
Embryonic period: week 5
- Ears, mouth, throat take shape
- Arm and leg buds appear
- Handplate from which fingers will emerge appears
- Heart divides into two regions
- Brain differentiates into forebrain, midbrain, and hindbrain
Embryonic - Week 6-7
- Embryo almost 1 inch long
- Heart divides into four chambers
- Fingers emerge from handplate
- Primative facial features evident
- Sexual differentiation begins
Embryonic - Week 8
- Most structures and organs present
- Ovaries and testies are evident
- Embryo begins to straighten and assumes more human appearance
Neural tube defects occur during which period
- during embryonic period – 25-29 days after conception
- 1 in 1000 pregnancies – neural tube fails to close completely
Spina bifida:
- Neural tube defect
- part of the spinal cord not fully encased in the protective covering of the spinal cord