Pregnancy complications Flashcards
What is an ectopic pregnancy
pregnancy implantation that occurs at another site other than the endometrium
Where are tubal pregnancies located
Most are located in the distal 2/3 of tube
What population is at highest risk of ectopic pregnancies
Black, non-hispanic
What is the biggest risk factor for ectopic pregnancies
50% have no risk factors
What are the risk factors for ectopic pregnancies
Prior ectopic
assisted reproduction
damaged fallopian tube
advanced maternal age
smoking
congenital tube defect
How do ectopic pregnancies present
abdominal pain and vaginal bleeding roughly 7 weeks after LMP
-can dx with TVUS and + serum HcG
Gestational sac can be seen by TVUS at what HcG level
> 1500
Gestational sac can be seen by trans abdominal US at what HcG level
> 3500
What is the medical management of an ectopic pregnancy
Methotrexate
*comparable to surgery
What is a tube saving surgical procedure for ectopic pregnancies
linear salpingostomy
What is a spontaneous pregnancy loss
non-viable intrauterine pregnancy with either an empty gestational sac OR gestational sac w/ embryo w/ no heart beat
When do most pregnancy losses occur
first trimester
What is the most common cause of spontaneous pregnancy loss
fetal chromosome abnormalities
If a mother is RH negative, what should be given
Rhogam
What is expectant management
Just wait things out and see what happens with the pregnancy
generally takes its course within 8 weeks
What HcG level is indicative of no pregnancy
<5
What is medical management of pregnancy loss
Intravaginal misoprostol
Which patients cannot have medical management of pregnancy loss
> 10weeks along
hemodynamically unstable
allergies to prostaglandins / NSAIDS
Anticoagulated patiens
infection
What is surgical management of pregnancy loss
Surgical evacuation preformed in the Office or operating room
What is gestational trophoblastic disease
Vaginal bleeding and enlarged uterus
How will gestational trophoblastic disease appear on US
Cluster of grapes
What rare complication can be evident by gestational trophoblastic disease
thyroid disease
What are the 2 types of gestational trophoblastic disease
Hydatidiform mole (molar preg)
Gestational trophoblastic neoplasia
What are the risk factors for gestational trophoblastic disease
extremes of age
hx of prior molar preg
hx os spontaneous preg loss
Can people have a normal pregnancy after a gestational trophoblastic disease
yes
What is a molar pregnancy
tumor that develops in the uterus as a result of a nonviable pregnancy
*generally non-cancerous
*can be complete or partial
What is gestational trophoblastic neoplasia
rare form of cancer
-choriocarcinoma
*placental-site trophoblastic tumor
What is the treatment for a molar pregnancy
surgical evaluation with D&C procedure (even if its a partial)
*if older = hysterectomy
also chemi/radiation
How long to woman have to wait to become pregnanct after a molar pregnancy
1 year
How long should HcG levels be monitored after a molar pregnancy
6 months
What are hypertensive disorders of pregnancy
gestational hypertension
preeclampsia
eclampsia
chronic HTN
chronic HTN w/ preeclampsia
How do you manage HTN in pregnancy if > 160/110
Mehtyldopa
labetolol
hydralazine
nifedipine
Which pregnant patients should labetalol not be used in
those with asthma or CHF
Which BP meds are contraindicated in pregnancy and why
ACEi
*Cause renal injury in 2nd/3rd trimester
What can be used for antenatal fetal surveillance
Non-stress test
US for fetal growth restriction
Biophysical profile
What is considered proteinuria in pregnancy
24 hour urine protein >300mg
Urine protein/creatinine >.3
What are severe feature of hypertension in pregnancy
severe HTN
Renal insufficiency
pulmonary edema
new onset HA**
visual disturbance
epigastric pain
impaired liver function
TTP>100,000
What is chronic HTN
Gestational BP elevated before the 20th week of gestation
*dx first time during pregnancy and doesn’t resolve postpartum
What is the most common cause of intrauterine growth restriction (IUGR)
Chronic HTN
What is gestational HTN
transient
*returns to normal by 12 weeks into post party period
HTN w/o proteinuria or severe features that develop after 20weeks
What is preeclampsia
New onset HTN and proteinuria dx after 20wks
OR
new onset HTN dx after 20 weeks with 1+ severe features
What are signs and symptoms of preeclampsia
LUQ / epigastric pain
persistent headache
hyperreflexia+/- clonus
occipital lobe blindness
What can be used to prevent preeclampsia
Low dose aspirin after 12 weeks gestation if at high risk for preeclampsia
What are the complications of preeclampsia
Seizure
hepatic dysfunction
DIC
Renal dysfunction
pulmonary edema
premature delivery
What is the only cure for preeclampsia
delivery… need to get placenta out
what is HELLP
Hemolysis
Elevated
Liver enzyme
Low
Platelets
When does HELLP present
antepartum or post partum
*preeclampsia variant
What is HELLP associated with
poor birthing person outcomes
*increased risk for pulmonary edema and acute renal failure
What is Eclampsia
New onset of grand Mal seizures in a patient with preeclampsia