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Endocrinology > Pregnancy again ... > Flashcards

Pregnancy again ... Flashcards

1
Q

Hormone produced in follicle growth?

A

Oestradiol

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2
Q

Hormone produced in fertilised ovum?

A

HCG

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3
Q

Hormone produced in corpus luteum?

A

Progesterone

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4
Q

Human placental lactogen
Placental progesterone
Placental oestrogen produced by what?

A

Placenta

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5
Q

Progesterones and hPL lead to what resistance in mother?

A

Insulin resistance

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6
Q

When does gestational diabetes present?

A

After 28 weeks

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7
Q

CNS defects in diabetes

A

Anencephaly, Spina bifida

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8
Q

Skeletal abnormalities in GD

A

Caudal regression syndrome

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9
Q

Genital and GI abnormalities in GD?

A

Ureteric duplication

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10
Q

Which makor growth factor is produced by foetus in the third trimester?

A

Insulin

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11
Q

What defines macrosomia?

A

BW>4kg

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12
Q

Supplement you give to diabetics in pregnancy?

A

Folic acid 5mg

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13
Q

Why do you give regular eye checks in pregnant diabetics?

A

Accelerated retinopathy

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14
Q

Which drugs should you avoid in pregnant diabetics?

A

ACEi’s and statins

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15
Q

How would you control blood pressure in pregnant diabetics?

A

Labetalol, nifedipine, methyldopa

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16
Q

Blood sugar aims? (pre-meal and post meal?)

A

pre-meal <7-8 mmol/l

17
Q

How do you maintain good blood glucose during labour?

A

IV insulin and IV dextrose

18
Q

Treatment for MODY?

A

Glibenclamide!!

19
Q

When should you carry out a post natal GTT?

A

6 week post natal GTT to ensure resolution

20
Q

How often should you carry out fasting glucose checks after someone with gestational diabetes has had a baby etc?

A

Annual fasting glucose

21
Q

hCG in hyperemesis gravidarum?

A

hCG HIGH

50-60% have abnormal TSH/fT4

22
Q

Hypothyroidism in pregnancy, how often should you check TFT’s?

A

Check TFTs montly for firs 20 weeks then 2 monthly until term

23
Q

TSH aim for hypothyroidism in pregnancy?

A

Aim for TSH < 3mU/L

24
Q

Untreated hypothyroidism risks in pregnancy?

A

Increased abortion, preeclampsia, abruption, postpartum haemorrhage, preterm labour,
Foetal neuropsychological development

25
Q

Gestational hCG-associated Thyrotoxicosis

A

Hyperemesis gravidarum –> increased hCG, decreases TSH
Resolves by 20 weeks gestation
Only treat if persists >20 weeks

26
Q

Hyperthyroid management in pregnancy?

A

beta blockers in early pregnancy
Propylthiouracil in 1st trimester
Carbimazole in 2nd/3rd trimester

27
Q

Risks of hyperthyroidism in pregnancy?

A

Stillbirth
Spontaneous miscarriage
Thyroid crisis during labour
Neonatal thyrotoxicosis

Endocrinology (30 decks)

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