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PSA > Pregnancy > Flashcards

Pregnancy Flashcards

1
Q

Which antibiotics are contraindicated in pregnancy?

A

Tetracyclines (tetracycline, doxycycline)
Aminoglycosides (gentamycin, streptomycin, neomycin)
Sulfonamides (sulfadiazine, sulfamethoxazole)
Trimethroprim
Quinolones (ciprofloxacin, norfloxacin)

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2
Q

Which antihypertensives are contraindicated in pregnancy?

A

ACEi

AngIIRB

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3
Q

Which antihypertensives are recommended in pregnancy?

A

Labetalol (1st line)
Methyldopa
Amlodipine/nifedipine

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4
Q

Which anti-epileptics are thought to be safer in pregnancy?

A

Aarbamazepine

Lamotrigene

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5
Q

Which antiepileptic is the worst in pregnancy?

A

Sodium valproate

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6
Q

Which diabetic drugs are contraindicated in pregnancy?

A

Sulfonylureas (gilclazide, gilbenclamide, glimepiride)

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7
Q

If a pregnant lady has a clotting disorder, what do they do?

A

Avoid warfarin

switch to LMWH

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8
Q

Effect of ACEi in pregnancy?

A

Teratogenic
Renal dysgensis
Craniofacial abnormalities

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9
Q

Effect of aminoglycosides in pregnancy?

A

teratogen: ototoxicity

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10
Q

Effects of antiepileptics in pregnancy?

A

Teratogen

Neural tube defects

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11
Q

Effect of chloramphenicol in pregnancy

A

grey baby syndrome

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12
Q

Effect of cocaine in pregnancy

A

IUGR, premature labour

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13
Q

Effect of poorly controlled DM?

A 
Macrosomia
Neural tube defects
Polyhydramnios
Prem labour
Shoulder dystocia
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14
Q

Effect of tetracyclines in pregnancy

A

Discoloured teeth

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15
Q

Effect of thalidomide in pregnancy

A

Limb reduction defects

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16
Q

Effect of warfarin in pregnancy?

A

Craniofacial abnormalities

17
Q

Which antibiotics should be avoided while breastfeeding?

A

Ciprofloxacin
Chloramphenicol
Tetracycline
Sulphonamides (sulfamethoxazole)

18
Q

Which psych drugs should be avoided while breastfeeding?

A

Lithium, benzodiazepines, clozapine

19
Q

Which heart drugs should be avoided while breastfeeding?

A

Amiodarone

Aspirin (Reye’s)

20
Q

Which laxative is 1st line in pregnancy?

A

Ispaghula husk

21
Q

When should contraceptive patches be avoided? (not combined hormonal contraception in general)

A

In those with BMI>35

Reduced efficacy if weigh >90kg

22
Q

What is the issue with drugs in the 1st trimester?

A 
Teratogenesis
Congenital malformations (esp 3-11weeks)
23
Q

What is the issue with drugs in the 2nd and 3rd trimester?

A

Growth and functional development of fetus

Toxic effect on fetal tissues

24
Q

Which drugs affect breastfeeding itself?

A

Phenobarbital reduces infant sucking reflex

Bromocriptine affects lactation

PSA (21 decks)

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