Pre-renal uremia vs. acute tubular necrosis Flashcards

1
Q

What is the main difference to remember between Pre-renal uremia vs. acute tubular necrosis?

A

In pre-renal uremia, the kidneys reabsorb the Na to try and hold on to water in an effort to dilute the urea in the blood.

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2
Q

What are the measurements comparisons for Pre-renal uremia vs. acute tubular necrosis?

Urine sodium	
Fractional sodium excretion
Fractional urea excretion
Urine:plasma osmolality
Urine:plasma urea
Specific gravity	
Urine	
Response to fluid challenge
A

Pre-renal uremia - ATN

Urine sodium : 30 mmol/L
Fractional sodium excretion*: 1%
Fractional urea excretion: 35%
Urine:plasma osmolality: > 1.5 10:1 1020

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