Practice Questions Flashcards
Doesn't include the antigram accompanied questions bc I'm not made of money
Which step of the elution procedure is different in comparing these three procedures: Lui-Freeze, Acid Elution and Heat Elution?
- Pre-Wash Step
- Process for Antibody removal from the cell
- Process for Antibody removal from the plasma
- Quality control step
Process for Antibody removal from the cell
The Lui-Freeze removes antibody through freezing the cell, The Heat Elution removes antibody by heating, and the Acid elution removes antibody by acifying the cell.
Which auto antibody is indicated when DAT results are positive with anti-C3d but negative with anti-IgG?
- Warm
- Cold
- Medication
- None
Cold
Complete the sentence:
(DAT/IAT)
detects antibody on the cell in vivo, while
(DAT/IAT)
puts antibody on cells in vitro.
Complete the sentence:
DAT detects antibody on the cell in vivo, while IAT puts antibody on cells in vitro.
True or False: Quality control results for a neutralization procedure should produce negative agglutination reactions with panel cells.
False
Which of the following is NOT an interpretation from a negative agglutination reaction?
- The Unit is compatible
- The Unit does not have the antigen
- The patient does not have the antigen
- The antibody is ruled in
The antibody is ruled in
Differentiate the properties of cold immune hemolytic anemias and warm hemolytic anemias.
- Hemolysis is Intravascular
- DAT result is typically IgG positive
- Purple extremities
- Most common specificity is anti-I
- Hemolysis is Extravascular
- Most common specificity is anti-e
- Reacts at AHG
- Extremely low hemoglobin values
- Reacts at IS
- DAT result is typically C3 positive
Sort charactersistic to correct group type: Warm or Cold
Cold:
* Reacts at IS
* Hemolysis is Intravascular
* DAT result is typically C3 positive
* Most common specificity is anti-I
* Purple extremities
Warm:
* Reacts at AHG
* Hemolysis is Extravascular
* DAT result is typically IgG positive
* Most common specificity is anti-e
* Extremely low hemoglobin values
Which test would most help you to distinguish if the cold antibody you have identified is benign or pathologic?
- Testing with a cord cell
- Test an enzyme treated panel
- Antibody Titer
- DAT
Antibody Titer
Which antibody is identified by the following serological results?
4C IS 37 AHG CC SC1 4+ 4+ 2+ 0 2+ SC2 4+ 4+ 2+ 0 2+ SC3 4+ 4+ 2+ 0 2+ Cord 0 0 0 0 2+
- anti-H
- anti-IH
- anti-i
- anti-I
Anti-I
Match the drug mechanism with its most severe drug.
Mechanism:
Drug Adsorption
Immune Complex
Membrane Modification
Drug Independent
Drug:
Aldomet
Cefotetan
Cephalosporin
Quinidine
Drug Adsorption - Cefotetan
Immune Complex - Quinidine
Membrane Modification - Cephalosporin
Drug Independent - Aldomet
If you have a DAT result that is IgG negative & compliment positive, and the serum in the sample is tea colored, what should you suspect is causing this?
- WAIHA
- Immune complex with a drug
- Darzalex
- Non specific cold agglutinin
Immune complex with a drug
Other than transfusion, what treatment might help a patient with an autoimmunehemolytic anemia?
- Plasma Exchange
- Antibody Titer
- Emergency Release of O negative blood
- Antibody Adsorption
Plasma Exchange
A positive Donath Landsteiner result indicates which diagnosis?
- WAIHA
- PCH
- PNH
- CAD
PCH
Which of the following components are acceptable to return to your blood bank inventory?
- I spiked un-used RBC with a temperature of 8C
- A RBC with a clot removed from the filter and temperature of 4.5C
- A RBC with an indicator dot that is red and a temperature of 2.3C
- A RBC out of blood bank for 30 minutes with a white temperature indicator and a temperature of 7.6C
A RBC out of blood bank for 30 minutes with a white temperature indicator and a temperature of 7.6C
Which of the following samples are acceptable for add-on crossmatch?
- 4 days old, A positive, negative screen
- 1 day old, O positive, positive screen
- 2 days old, B positive, no current screen results available
- 3 days old, AB negative, negative antibody screen with history of anti-Fya
Select all that apply
- 1 day old, O positive, positive screen
- 3 days old, AB negative, negative antibody screen with history of anti-Fya
Choose all that apply: Under which circumstance would you warm a crossmatch?
- A negative, negative antibody screen, positive IS crossmatch
- O positive, anti-M identified
- O negative, anti-D identified
- ABO discrepancy with extra reaction in the reverse type
- A negative, negative antibody screen, positive IS crossmatch
- O positive, anti-M identified
