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BB final > AutoClots, Roll Out > Flashcards

AutoClots, Roll Out Flashcards

1
Q

Extravascular Autoimmune Hemolysis

A

Warm Auto

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2
Q

Intravascular Autoimmune Hemolysis

A

Cold Auto (also technically extravascular but the Practice Questions marked Intravascular as correct 🤷‍♂️)

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3
Q

Warm Autoimmune Specificity

A

Frequently Rh

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4
Q

Cold Autoimmune Specificity

A

Frequently I or P

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5
Q

DAT: IgG+ & C3d+/-

A

Warm Autoimmune

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6
Q

DAT: IgG- & C3d+

A

Cold Autoimmune

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7
Q

Autoimmune Type that Binds Compliment

A

Cold Autoimmune

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8
Q

Tea Colored Plasma

A

Drug-Induced Antibody

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9
Q

Cefotetan

A

Drug-Adsorption

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10
Q

Streptomycin

A

Drug-Adsorption

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11
Q

Penicillin

A

Drug-Adsorption

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12
Q

Drug-Adsorption Detection Findings

A

DAT: IgG+, C3d -
Eluate: Negative
Diagnosis: Eluate and ABID Positive with drug coated panel cells only.
Hemolysis: Yes
(Extravascular&raquo_space; Intravascular)

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13
Q

Quinidine

A

Immune Complex

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14
Q

Phenacetin

A

Immune Complex

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15
Q

Immune Complex Detection Findings

A

DAT: IgG+/-, C3d +
Eluate: Negative
Diagnosis: Pt Serum + Drug + ABO Compatible Cells = Hemolysis
Hemolysis: Yes (Intravascular)

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16
Q

Cephalosporin

A

Membrane Modification

17
Q

Membrane Modification Detection Findings

A

DAT: IgG+, C3d +
Eluate: Negative
Diagnosis: Everything else ruled out
Hemolysis: No

18
Q

Alpha-Methyldopa “Aldomet”

A

Drug Independent

19
Q

Drug Independent Detection Findings

A

DAT: IgG+
Eluate: Positive with all cells
Diagnosis: History of the drug
Hemolysis: Yes (Mimics WAIHA)

20
Q

Darzalex

A

Chemo Drug

21
Q

-umab (Human Monoclonal Antibodies)

A

Chemo Drug

22
Q

Chemo Drug Detection Findings

A

DAT: Weak Positive Poly & IgG
Eluate and ABID: Positive with all cells and auto control
Diagnosis: DTT treatment removes the antigen and the ID becomes negative

23
Q

Benign Cold Agglutinins

A

Anti-i
Anti-I
Anti-IH

24
Q

Pathologic Cold Agglutinins

A

PCH
CHD

25
Q

CHD Antibody

A

Anti-I, Wide Thermal Range IgM

26
Q

PCH Antibody

A

Donnath-Landsteiner IgG specificity to Anti-P

BB final (9 decks)

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