Practice Exam Questions Flashcards

1
Q

Which category of the Vaughan Williams classification is amioderone classed as?

A

III

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2
Q

Which of the following conditions is a low molecular weight heparin not used for?

a) adjunct to thrombolysis
b) DVT prophylaxis
c) DVT/PE treatment
d) unstable coronary syndrome

A

It is not used adjunct to thrombolysis

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3
Q

Calcium channel agonists block which channel?

A

L

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4
Q

Flecainide, a class 1 antidyshythmics drug, is used clinically to….

A

Prevent paroxysmal atrial fibrillation

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5
Q

An example of a type A adverse drug reaction would be:

a) Anaphylaxis with anoxicillin
b) steven jonsons syndrome with carbamazepine
c) bradycardia with digoxin
d) hyperglycaemia with sulphonylureas

A

Bradycardia with digoxin

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6
Q

Which one of the following is an important enzyme inducer

a) cranberry juice
b) cigarette smoke
c) grapefruit juice
d) ferrous sulphate

A

Cigarette smoke

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7
Q

A potential adverse effect of sulphonylureas is:

a) flatulence and bloating
b) hypoglycaemia due to insulin over secretion
c) hyperglycaemic due to insulin over secretion
d) hypoglycaemia due to under secretion

A

Hypoglycaemia due to insulin over secretion

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8
Q

Which one of the following is not an indication for urgent endoscopy

a) dysphasia
b) progressive unintentional weight loss
c) iron deficiency anaemia
d) pt <55 without alarm symptoms

A

Oh <55 without alarm symptoms

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9
Q

Which of the following drugs will not cause dyspepsia

a) slidenafil
b) amlodipine
c) celecoxib
d) bisoprolol

A

Bisoprolol

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10
Q

Which of the following drugs is least likely to exacerbate asthma

a) propranolol
b) ibuprofen
c) aspirin
d) domperidone

A

Domperidone

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11
Q

Which one of the following is not an unwanted effect of statin use

a) myalgia
b) peripheral neuropathy
c) altered liver function test
d) bleeding

A

Bleeding

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12
Q

Which of the following factors is least likely to put paitents at high risk of bleeding when taking warfarin

a) diarrhoea
b) liver disease
c) instability of INR
d) age >75

A

Diarrhoea

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13
Q

Warfarin affects the synthesis of clotting factors

A

2/7/9 and 10

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14
Q

Which of the following is least likely to indicate a diagnosis of COPD

chronic cough
Exertional breathlessness
Smoker /ex smoker
Significant day to day variability in symptoms

A

Significant day to day variability in symptoms

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15
Q

What cycle of the myocyte action potential does verapamil act on

A

2

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16
Q

The half life of adenosine is approximately what?

A

10seconds

17
Q

Which bacteria is typically associated with an increased risk of peptic ulcer

A

Helibactor pylori

18
Q

What type of drug is salbutamol

A

Beta 2 agonist

19
Q

Suspected adverse drug reaction should be reported through what system

A

Yellow card system

20
Q

Therapeutic effect of low-molecular weight heparin can be described as:

A

Anticoagulant

21
Q

Potency is what

A

The magnitude of effect following a drug- receptor interaction

22
Q

Which of the following is likely to cause hypoglycaemia in the elderly

Glilbenclamide
Glicazide
Metformin
Glucagon

A

Glibenclamide

23
Q

A drug that is a P450 enzyme inducer will typically

A

Increase the metabolism of other drugs

24
Q

Which of the following is not associated with serotonin syndrome

Agitation
Bradycardia
Tremor
Hyperthermia

A

Bradycardia

25
Q

SSRIs are contraindicated in

Patients who have had a MI
patients <21
Patients who are epileptic
Patients <18

A

Patients who are <18

26
Q

Which group are typically most at risk from adverse drug reactions

Middle aged adults living in the community
Community dwelling older people
Older in residential care
Teenagers living in the community

A

Older in residential care

27
Q

Which of the following is not an unwanted side effect of morphine

Constipation
Analgesia
Nausea
Drowsiness

A

Analgesia

28
Q

An adverse drug reaction is defined as:

A

A response to a drug which is noxious and unintended

29
Q

First dose hypotension is associated with

Calcium channel blockers
Beta blockers
ACE inhibitors
Statins

A

ACE inhibitors

30
Q

Low density lipoproteins transport lipids to …

A

Adipose tissue for storage