Practice Flashcards
Punctuate hemorrhages are indicative of
DAI
General Category
of Neurodegenerative Disease
Alzheimer’s
Picks
Parkinson’s
Huntington’s
Alzheimer’s- Tauopathy
Picks- Tauopathy
Parkinson’s- Synucleinopathy
Huntington’s
Brain sites of Early Involvement
Alzheimer’s
Picks
Parkinson’s
Huntington’s
Alzheimer’s- Narrowing gyri, diffuse
Picks- Frontal/ temporal
Parkinson’s: Substantia Nigra
Huntington’s- Caudate
Characteristic Neuropathological Features
Alzheimer’s: Neurofibrillary tangles, neuritic plaques
Picks- Pick bodies
Parkinson’s- Lewy Body
Huntington’s
Genetics:Strong Familial Tendency?
Alzheimer’s- Presinillin: young (chromo 21)
APOE4- older
Picks
Parkinson’s
Huntington’s: CAG on chromo 4
Most Common Age
Medulloblastoma Glioblastoma Pilocytic Meningioma Ependymoma
Medulloblastoma
Glioblastoma
Pilocytic
Meningioma
Ependymoma
Most Common Anatomical Site
Medulloblastoma Glioblastoma Pilocytic Meningioma Ependymoma
Medulloblastoma: Cerebellar vermis
Glioblastoma
Pilocytic
Meningioma
Ependymoma: Spinal cord, 4th ventricle
WHO Grade
Medulloblastoma Glioblastoma Pilocytic Meningioma Ependymoma
Medulloblastoma
Glioblastoma: WHO Grade IV
Pilocytic
Meningioma
Ependymoma
Most metastases do not present with
hemorrhage
ischemic stroke is most likely to transform into a hemorrhage
Embolic stoke
Barbiturate
Barbiturates are drugs that act as central nervous system depressants, and can therefore produce a wide spectrum of effects, from mild sedation to total anesthesia. They are also effective as anxiolytics, hypnotics, and anticonvulsants.
