Practice

Question 1

What is medicines reconciliation?

Answer 1

The process of identifying an accurate list of a persons current medications and comparing them with the current list in use, recognising any discrepancies, and documenting any changes.

Question 2

In an acute setting when should medicines reconciliation take place?

Answer 2

Within 24 hours or sooner if clinically necessary

Question 3

When should medicines reconciliation take place in primary care?

Answer 3

As soon as practically possible, before a new prescription is issued. Within one week of the GP practice receiving the information.

Question 4

Aims of the 1971 misuse of drugs act?

Answer 4

Sort out existing fragmentary, inadequate and inflexible legislation
Advisory council on misuse of drugs was established
Imposes a total prohibition on the possession, supply, manufacture, import or export of controlled drugs and except as allowed by misuse of drugs regulations or under a home office license

Question 5

How are drugs classified by the misuse of drugs act?

Answer 5

According to potential harm
In classes A,B and C

Question 6

How are drugs classified by the misuse of drugs regulations?

Answer 6

According to their use in medicine and potential abuse
In schedules

Question 7

What strength of morphine can be schedule 5?

Answer 7

0.2% or less

Question 8

Another name for class 1 medicines recall?

Answer 8

National patient safety alert

Question 9

Timeframe to action class 1 medicines recall?

Answer 9

Immediately upon receipt

Question 10

Timeframe to action class 2 medicines recall?

Answer 10

Within 48 hours

Question 11

Timeframe to action class 3 medicines recall?

Answer 11

5 days

Question 12

Definition of asepsis?

Answer 12

Absence of bacteria, viruses, and other microorganisms

Question 13

What is good manufacturing practice?

Answer 13

Compliance ensures products are produced consistently to the quality standards appropriate to their community intended use

Question 14

What are the two types of aseptic activities?

Answer 14

Licensed manufacture
Unlicensed preparation

Question 15

What is aseptic licensed manufacture?

Answer 15

Allows manufacturing of a product that doesn’t have a product licence or marketing authorisation
Potential to sell to external customers
Assign extended expiry dates to products provided they are supported by stability data

Question 16

What is aseptic unlicensed preparation?

Answer 16

Prepare aseptic products under an exemption from a section 10 of the medicines act 1968

Question 17

What conditions need to be met to operate under an exemption from section 10?

Answer 17

Preparation done by or under supervision from a pharmacist
Preparation uses closed systems
Licensed sterile products used as ingredients
Allocated a maximum of 7 days expiry
All activities in accordance with defined NHS guidelines

Question 18

What legislation must licensed aseptic units comply with?

Answer 18

EU guide to good manufacturing practice (orange guide)

Question 19

What legislation must unlicensed aseptic units comply with?

Answer 19

NHS guidance: quality assurance of aseptic preparation services
Good practice to comply with orange guide

Question 20

Quality assurance definition?

Answer 20

The sum total of all the organised arrangements made with the objective of ensuring that medicinal products are of the quality for the intended use

Question 21

What are positive pressure isolators used for?

Answer 21

Parenteral nutrition and civas products
In event of isolator breach air will leave the isolator
Product protection takes priority over operator protection

Question 22

What are negative pressure isolators used for?

Answer 22

Cytotoxic and monoclonal antibody products
In event of isolator breach air will enter the isolator
Operator protection takes priority over product protection

Question 23

How are ingredients decontaminated in an aseptic unit?

Answer 23

Four step wipe and spray process