prac1 Flashcards
describe simple Squamous epithelium
- flat, irregularly shaped, tightly-fitted cells in a mosaic like pattern with flattened centrally located nucleus
function of simple Squamous epithelium
diffusion and filtration
location of simple Squamous epithelium
pulmonary alveoli, kidneys, lining the inner walls of blood and lymphatic vessels (endothelium), form serous membranes that line the body cavities and its organs – pericardium, pleura, peritoneum
describe simple cuboidal epithelium
- composed of tightly fitted cube-shaped cells, with centrally positioned round nucelus
FUNCTION of simple cuboidal epithelium
secretion, filtration and absorption
LOCATION of simple cuboidal epithelium
found in many glands and glandular organs and ducts (e.g. surface of ovaries, ducts of salivary glands and pancreas)
describe simple columnar epithelium
- Composed of tall, columnar cells (height caries), tightly fitted, nucleus usually located close ot the basement membrane; goblet cells
- Non-ciliated (covered in microvilli to increase SA for absorption in intestine)
- Ciliated (covered in cilia to support beating of secondary oocyte through the uterine tube to the uterus)
what are the two types of simple columnar epithelium
ciliated
non-ciliated
what is non-ciliated simple columnar epithelium covered in and why
covered in microvilli to increase SA for absorption in intestine
what is ciliated simple columnar epithelium covered in and why
covered in cilia to support beating of secondary oocyte through the uterine tube to the uterus)
function of simple columnar epithelium
protection, lubrication, secretion and absorption
location of simple columnar epithelium
lining of intestine, uterine tubes, bronchioles
describe pseudo-stratified simple epithelium
- cells are of different heights with a variable position of the nucleus giving the appearance of being stratified; goblet cells
- non-ciliated(rare) or ciliated
what are the two types of pseudo-stratified simple epithelium
non-ciliated
ciliated
function ciliated Pseudo-stratified simple epithelium
ciliated= protection, secretion of mucin, movement of particles and mucus
function non-ciliated Pseudo-stratified simple epithelium
protection
location of ciliated pseudo-stratified simple epithelium
ciliated: trachea, bronchi, nasal cavity
location of non-ciliated pseudo-stratified simple epithelium
non-ciliated: male urethra, male epididymis (sits on top of testes, where sperm matures)
describe stratified Squamous epithelium
- apical surface cells are squamous while the cells closer to the underlying connective tissue are cuboidal to columnar
function of stratified Squamous epithelium
found in areas subjected to wear and tear; top layer cells are rubbed away and replaced via mitosis of the innermost cells
what are the two types of of stratified Squamous epithelium
keratinised
non-keratinised
location of keratinised stratified Squamous epithelium
keratinised (dry) contains keratin, a protein that strengthens the tissue, LOCATION: epidermis
location of non-keratinised stratified Squamous epithelium
non-keratinised (wet) mucosa; LOCATION: mouth, oesophagus, larynx, vagina, anal canal
describe stratified cuboidal epithelium
- rare
- usually only two or three layers of cuboidal cells
function of stratified cuboidal epithelium
protection, secreition
location of stratified cuboidal epithelium
LOCATION: ducts of sweat glands
describe stratified columnar epithelium
- rare
- basal layer – short cells of irregular shape, apical cells columnar
function stratified columnar epithelium
protection, secretion
location of stratified columnar epithelium
conjunctiva, large ducts of salivary glands
describe transitional columnar epithelium
- characterised with cells that change form according ot the degree of distension – flat (squamous) when stretched and cuboidal when relaxed
function of stratified transitional columnar epithelium
protection, distensibility
location of stratified transitional columnar epithelium
lining the cavity of urinary bladder, ureters,
function of connective tissue
- provides structural and metabolic support to other
* tissues: protection, transport, repair, storage
what does fibroblasts synthesise?
- synthesise collagen, elastic and reticular fibres, and extracellular matrix
what are fibroblasts responsible
wound healing
describe adipocytes
o specialised for fat storage, energy and insulation; involved in the synthesis of hormones and growth factors
o act as a cushion for organs e.g. heart and kidney
o located throughout loose connective tissue
o Cytoplasm with flattened nucleus forms a very narrow rim around a large central lipid droplet
o Produces the hormone leptin – which is responsible for satiety/fullness – leptin controls nutrient homeostasis
describe macrophages
o Develop from monocytes in bone marrow – (WBC)
o Irregular shape, short branched projections
o Destroys bacteria and cellular debris (phagocytosis)
o Fixed and wandering
o Contains lots of lysosomes to help break down debris, virus etc.
o Immune/defence cells
describe mast cells
o Immune cell that develop in bone marrow, differentiate in connective tissues
o Function: inflammatory and allergic response (granules contain histamine, heparin), kill bacteria
what is the extracellular matrix made up of
ground substance
collagen fibres
elastic fibres
reticular fibres
describe ground substancce
o Fluid, semi-solid, solid
o Space between cells and fibres
o Consists of water and complex carbohydrates and glycoproteins – contains hydrolonic acid (helps phagocytes to move through connective tissue)
o Hylaronidaise is produced by WBC and sperm cell – makes hydrlinic acid more permeable
o In sperm cell hydralonidaise to breakdown hydralonic acid to allow the sperm cell to enter the egg for fertilisation
Function: mechanical and structural support for tissue; biochemical barrier-role in regulating metabolic functions in surrounding cells
describe collagen fibres
o Strongest fibres (stronger than steel fibres of the same size)
o Most abundant type: closely packed orderly, flexible, high, tensile strength
o Made of collagen protein
o Types:
1. Skin, bones, tendons, organs capsules
2. Hyaline and elastic cartilage
3. Organs, smooth muscle
4. Associated with basal lamina of the basement membrane of epithelial cells (support, filtration)
describe elastic fibres
o Thin, elastic allows tissue to respond to stretch and distensions; located in skin, lung and bladder
o Elastin surrounds glycoprotein allowing the tissue to stretch and recoil
describe reticular fibres
o Very thin, type 3 collagen associated with high levels glycoprotein
o Provides a supporting framework for the cellular constituents of various tissues and organs
o E.g. in basement membrane
list the types of connective tissue proper
loose connective tissue - areolar - adipose - reticular dense connective tissue - dense regular - dense irregular -elastic
describe loose connective tissue areola
o Very thin, type 3 collagen associated with high levels glycoprotein
o Provides a supporting framework for the cellular constituents of various tissues and organs
o E.g. in basement membrane
describe loose reticular connective tissue
o intertwining reticular fibres
o creates a network that forms the stroma, binds smooth muscle cells; reticular fibres filter blood and lymph
o makes up bone marrow…
describe adipose tissue
o consists of mostly adipocytes
o location subcutaneous, around organs e.g. heart, kidney, yellow marrow of long bones
o function: insulation, energy reserve and protection and support
o great for nutrient storage
o responsible for removing lipids from blood stream
o more adipose tissues=body creates extra blood vessels
o in the messentary - anchors small intestine to abdominal wall (in pertineoum)
o 2 different types – white (insulation, energy reservation…) and brown (only found in 3 locations anterior neck, anterior abdominal wall, between scapulae – great ability for thermogenesis)
function of adipose tissue
nsulation, energy reserve and protection and support
o great for nutrient storage
describe dense regular connective tissue
o Abundant collagen fibres, few cells and little ground substance
o Well aligned densely packed fibres collagen arranged in bundles – fibroblasts arranged in rows between collagen bundles
location of dense regular connective tissue
tendons, ligaments, aponeuroses and capsules of organs
function of dense regular connective tissue
o FUNCTION: strong attachment between structures
o With strands great strength if only pulled in one direction
describe dense irregular connective tissue
o Mostly collagen fibres, few cells and little ground substance
o Tightly packed fibres random in 3dimesions – can withold being pulled in different directions
location dense irregular connective tissue
the dermis (reticular or deep layer) and digestive tract (submucosa)
function dense irregular connective tissue
o FUNCTION: strength, resists stretch/tearing in multiple directions
describe elastic connective tissue
o Predominantly elastic fibres; fibroblast in the spaces between the fibres
o Yellowish in colour, stretching capability; lungs, elastic arteries some ligaments
o E.g. in lungs, aorta
what are the two types o fcartilage
hyaline
fibrocartilage
location of hyaline cartilage
at ends of long bones, anterior ends of ribs, nose parts of larynx, trachea
function of hyaline cartilage
cushioning,
creates a smooth low friction surface for joints
provide flexibility and support in respiratory system, frame for ossification (epiphyseal plste)
what are the two main materials in hyaline cartilage
chondrocytes
collagen
what is fibrocartilage made of?
combination of dense regular connective tissue and cartilage
location of fibrocartilage
o LOCATION:pubic symphysis, intervertebral discs, menisci of knee
function of fibrocartilage
o FUNCTION: support and fusion, resists deformation under stress
how many bones
206
what are the two classifications of bone tissue
compact , spongy
function of bones
support movement protection mineral storage
blood cell formation
energy storage
what are the 5 classifications of bones?
long short flat irregular wormian
describe long bones
longer than they are wide
e.g. of long bones
humerus radius ulna pahalanges femur
describe the diaphysis
shaft (diaphysis) – a cylinder of compact bone around the inner(medullary cavity, outer surface surrounded by a layer of connective tissue – periosteum, nutrient foramen
where is the epiphysis located
- Epiphysis – end of the bone, spongy tissue, red bone marrow, articular cartilage
location of metaphysics in bones
- Metaphysis – between diaphysis and epiphysis, in growing bone contains epiphyseal (growth) plate of hyaline cartilage (longitude growth), becomes epiphyseal line
e.g.s of short bones
carpals, tarsals
describe short bones
nearly equal in length and width
describe sesamoid bones
- Develop in tendons as a response to physical stress; not always completely ossified
e.g.s of sesamoid bones
patella, pisiform
describe flat bones
• Two surface layers of compact bone and spongy bone in the centre is called diploë
e.g. of flat bones
• E.g. cranial bones, ribs, scapulae
e.g. of irregular bones
vertebrae, calcaneus, facial bones
where is the frontal bone located
front of cranium
where is the parietal bones located
Theupper sides and rood of the craium
Articulations form sutures:
- Coronal suture between frontal and parietal bones
- Sagital suture between parietals meet tempporals
- Squamous suture parietals meet temporals
- Lamboid suture where parietals meet occiptal
where is the temporals bone located
Squamous part (zygomatic process – zygomatic arch)
Tympanic part (external acoustic meatus – ear canal)
Petrous part (the floor of the cranium)
Styloid process (projects inferiorly)
Mastoid process (can be used in sex determination)
where is the occipital bone located
The posterior and most of the base of the skill
Lambdiod suture (parietals)
Foramen magnum (spingal cord)
Occiptal condyles
where is the sphenoid bone located
Part of the anterior and middl eportions of the base of the craium and orbit
The body (sinus) and laterally projectign greater and lesser wings
where is the ethmoid bone located
The anterior portion of the floor of the cranium between the orbits, roof and superior sidewalls of the nasal cavity, spetum
ethmoid sinus
Superior andmiddle nasal conchae- scross shaped plates of bone
Humidifys air preparing it to go in the lungs
where is the fontaelles bone located
Plates of cartilage (mesenchyme):
- Anterior (1) between parietals and frontal (fuse 18-24 months)
- Posterior (1) between parietals and occiptal (fuse 2-3 months)
- Anterolateral (2) between frontal, parietal, temproal and sphenoid (fuses at 6 months)
- Posterolateral (2) between parietal, occiptal and temporal (fuse 6-18 month)
- Allows for baby to be birthed via pelvis – allows skull ot be manipulated and moved to birth – then fuse later
what are the three large distinct depressions
- The anterior cranial fossa: the frontal bone (anteriorly), ethmoid (middle), body and lesser wings of sphenoid (posteriorly)
- The middle cranial fossa: sella turcica (medially), greater wings of sphenoid, squamous (laterally) and petrous (posteriorly) parts of temporal
- The posterior cranial fossa: mainly occiptal
where is the maxilla
upper jaw
locate the palatine bone
top of mouth
locate zygomatic bone
cheekbones
• Lateral contours of the face, lateral margin of the orbit
• Temporal process and zygomatic process (temporal)= zygomatic arch
• Defines inferior margin orbit
locate lacrimal bone
tear ducts
The anterior part of the medial wall of the medial wall of the orbit
• Smallest facial bone
• Has a duct/hole which drains tears
locate the vomer
- Thin, flat, forms the lower part of the nasal cavity (below superior and middle nasal conchae)
- Component of nasal septum along with septal cartilage and perpendicular plate
locate the mandible
lower jaw
- Largest strongest facial bone
• Condylar process (forms main portion of a moving joint) vs. coronoid process
locate hyoid bone
• Not attached directly to any other bone
- Located in the neck inferior to mandible
- Suspended from the styloid process by the stylohyoid muscles and ligaments
- Supports and acts as a moveable base for the tongue
list the regions of the vertebrae
- Regions: cervical 7, thoracic (12), lumbar (5), sacrum (5 fused), coccyx(4 fused)
list the curves of the vertebrae
- Cervical (convex, secondary)
- Thoracic (concave, primary)
- Lumbar (convex, secondary)
- Sacral (concave, primary)
describe the cervical vertebrae
- Spinous process is unique to cervical vertebra
- C1 and C2 are ATYPICAL
- C3-C7 TYPICAL
- Vertebra within neck
- 7 vertebrae
describe the thoracic vertebrae
- 12 which articulate with the 12 ribs
- Transverse processes make contact with ribs and allow for ligament and tendon
- Foramen is where spinal cord travelst hrough
- 12 vertebrae
describe the lumbar vertebrae
- Largest
- Bears the most weight
- Thick body, wider
- Oval foramen
- 5 vertebrae