PQS - Mycobacterium ✅ Flashcards

1
Q

Giant cells typically occur in tubercles

A

T

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2
Q

Mycobacterium tuberculosis can cause generalised tuberculosis in pigs.

A

T

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3
Q

Mycobacterium tuberculosis can cause tuberculosis in humans.

A

T

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4
Q

Facultative pathogenic mycobacteria can colonise only cold-blooded animals.

A

F

Cold-blooded, cattle and swine + other mammals

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5
Q

Mycobacteria are facultative intracellular bacteria.

A

T

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6
Q

Saprophytic and facultative pathogenic mycobacteria cannot colonise warm blooded animals.

A

F

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7
Q

Facultative pathogenic Mycobacteria can only reproduce in the environment.

A

F

Can be found in environment, plants, water and gut
Can also replicate in animals, but the environment is the main way

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8
Q

Facultative pathogenic Mycobacteria can only colonize in warm-blooded animals.

A

F

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9
Q

There is no antigen connection between facultative and obligate pathogenic mycobacteria

A

F

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10
Q

Pigs are resistant against Mycobacterium tuberculosis.

A

F

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11
Q

Lympho-haematogenous spread of mycobacteria can be seen in the post primary phase of tuberculosis.

A

F

Found in phase 2 - “early generalization”

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12
Q

There is a close antigen relationship between mycobacteria

A

T

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13
Q

Mycobacterium bovis can cause tuberculosis only in ruminants

A

F

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14
Q

Mycobacterium bovis can cause generalized tuberculosis in goats

A

T

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15
Q

Tuberculin is an extract made from broth culture of mycobacteria

A

T

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16
Q

The tuberculin contains antigens from mycobacteria

A

T

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17
Q

Tuberculin is the toxin produced by mycobacteria

A

F

it’s an antigen extract

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18
Q

Intra canalicular spread of mycobacteria can be seen in the post primary phase of
tuberculosis

A

T

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19
Q

Antibodies against mycobacteria are detected in the tuberculin test

A

F

Measure the immune response, measuring the reaction of skin

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20
Q

Facultative pathogenic mycobacteria can cause local lesions in pigs

A

T

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21
Q

Facultative pathogenic mycobacteria cannot cause tuberculosis

A

F

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22
Q

Mycobacteria are acid and alcohol fast bacteria

A

T

= the bacteria is resistant to acid and alcohol

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23
Q

Mycobacterium tuberculosis can cause generalized tuberculosis in parrots

A

T

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24
Q

Fresh tuberculosis lesions in the lymph nodes are common the early generation

A

T

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25
Q

Mycobacteria can be stained with Ziehl-Neelsen staining

A

T

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26
Q

Mycobacteria cannot be stained

A

F

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27
Q

Obligate pathogenic mycobacteria can occur and replicate in the environment

A

F

Replicates in the infected animal

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28
Q

All mycobacteria species are obligate pathogenic

A

F

Majority is, but some are saprophytic, facultative pathogens

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29
Q

The resistance of mycobacteria is low, they die in the environment soon

A

F

Certain components make the cell wall very resistant

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30
Q

Mycobacterium bovis can cause generalised tuberculosis in goats

A

T

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31
Q

Fresh tuberculosis lesions in the lymph nodes are common in the post primary phase

A

F

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32
Q

Mycobacteria are highly resistant thanks to lipids and waxes in the cell wall

A

T

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33
Q

Mycobacterium tuberculosis can cause tuberculosis in humans

A

T

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34
Q

Mycobacterium tuberculosis can cause generalized tuberculosis in pigs

A

T

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35
Q

Mycobacterium bovis can cause generalized tuberculosis in pigs

A

T

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36
Q

Pigs are resistant against Mycobacterium tuberculosis

A

F

They are highly susceptible

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37
Q

Mycobacterium bovis can cause generalized tuberculosis in badgers

A

T

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38
Q

Mycobacterium caprae can infect only goats

A

F

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39
Q

Tuberculosis lesions in the lymph node are common in the early generalization

A

T

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40
Q

The habitat of the obligate pathogenic Mycobacteria is the environment

A

F

habitat is the infected animal

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41
Q

Mycobacteria are obligate intracellular bacteria

A

F

= Facultative intracellular bacteria

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42
Q

Waxes can be found in the cell wall of Mycobacteria

A

T

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43
Q

Only Mycobacterium tuberculosis can cause tuberculosis in humans

A

F

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44
Q

Neutrophil granulocytes can be typically found in tubercles

A

F

Lymphocytes are found

45
Q

Necrosis can be seen in the tubercles

A

T

46
Q

The habitat of saprophytic, facultative pathogenic Mycobacteria is the environment.

A

T

Together with plants, water and gut

47
Q

Saprophytic, facultative pathogenic Mycobacteria cannot colonize mammals

A

F

48
Q

Mycobacteria have several shared antigens

A

T

49
Q

The cell wall of mycobacteria contains mycolic acid

A

T

50
Q

The tuberculin contains lipopolysaccharide (LPS) antigens

A

F

51
Q

The cell wall of mycobacteria contains large amount of lipopolysaccharide

A

T

52
Q

Mycobacteria can replicate only in animals

A

T

F??

Different species, different habitats:

1. Obligate pathogenic = animals

2. Saphrophytic, facultative pathogenic = environment, plants, water, gut

53
Q

Mycobacterium tuberculosis causes tuberculosis in parrots

A

T

54
Q

Mycobacterium tuberculosis causes generalized tuberculosis in badgers

A

F

M.bovis does

55
Q

Mycobacterium tuberculosis causes tuberculosis in poultry

A

F

Cage birds and parrots, NOT poultry

56
Q

The cell wall of mycobacteria contains mycolic acid

A

T

57
Q

The tuberculin contains lipopolysaccharide (LPS) antigens

A

F

58
Q

All mycobacteria can replicate in the environment

A

F

59
Q

Mycobacterium bovis can cause tuberculosis in wild living ruminants

A

T

60
Q

Mycobacterium bovis can cause tuberculosis in wild boars

A

T

61
Q

If the increase of the thickness of the skin fold in the tuberculin test is 1.9 mm the
reaction is positive

A

F

Less than 2mm = negative

62
Q

The skin intradermal tuberculin test is a Type IV. hypersensitivity reaction

A

T

63
Q

Antigens of mycobacteria show a close relationship

A

T

64
Q

Mycobacteria can survive in the environment only for a few days

A

F

65
Q

Atypical mycobacteria can cause lesions in pigs

A

T

66
Q

Mycobacteria caprae can infect cattle, other ruminants and swine.

A

T

67
Q

Saprophytic, facultative pathogenic mycobacteria cannot cause tuberculosis

A

F

But not very common

68
Q

Only cattle maintain bovine tuberculosis

A

F

69
Q

Obligate pathogenic Mycobacteria can only reproduce in the infected body

A

T

70
Q

Facultative pathogenic mycobacteria can cause tuberculosis in fishes

A

T

71
Q

Mycobacteria are not resistant, they can survive in the environment for maximum of two days

A

F

Due to the cell wall components, they survive long

72
Q

Mycobacterium suis is the most frequent agent of tuberculosis of pigs

A

F

M.bovis and M.Caprae is most common

73
Q

Facultative pathogenic mycobacteria can colonize the gut of pigs

A

T

74
Q

Sometimes facultative pathogenic mycobacteria cause lesions in pig

A

T
Local lesions

75
Q

Mycobacteria can survive in the environment

A

T

76
Q

Mycobacteria cannot be cultured

A

F

77
Q

Waxes and lipids in the mycobacteria are virulence factors

A

T

78
Q

The agent of avian tuberculosis is an obligate pathogenic bacterium.

A

T

79
Q

Tuberculin test is an allergic test

A

T

80
Q

Mycobacteria can be cultured, but their incubation time is long

A

T

81
Q

Tuberculosis is diagnosed by detecting antibodies to M. bovis in the blood with ELISA

A

F

Used as complimentary test

82
Q

The center of the tubercle is necrotized

A

T

83
Q

The tubercle consists of histiocytes and foreign body giant cell.

A

T

84
Q

The causative agents of tuberculosis are obligate pathogenic bacteria

A

T

85
Q

Köster staining is a special staining for Mycobacteria

A

F

Ziehl-Neelsen

86
Q

Mycobacteria are highly resistant

A

T

Due to the cell wall

87
Q

Early generalization of mycobacteria occurs via lympho-hematogenous route

A

T

4.phases:
1. Primary focus
2. Early generalization
3. Post primary phase
4. Late generalization/exhaust phase

88
Q

In dogs’ tuberculosis can be generalized

A

T

89
Q

Late generalization can be characterized by lost resistance.

A

T

90
Q

In the tubercle, coagulation necrosis is seen.

A

T

91
Q

In the phase of early generalization Mycobacteria do not replicate in the lymph node.

A

F

92
Q

Mycobacteria are a worldwide disease

A

T

93
Q

Chronic tuberculosis causes changes in the lymph node

A

F

No fresh lesions in the lymph nodes

94
Q

Mycobacteria can be demonstrated from the discharge of sick animals by staining.

A

T

95
Q

Tuberculosis can be demonstrated earliest by ELISA

A

F

96
Q

Tuberculosis can first be diagnosed by PCR

A

F

97
Q

Tuberculosis can be diagnosed with certainty serology

A

F

98
Q

Mycobacterium infection in pigs can be zoonotic

A

T

99
Q

Mycobacterium spp. in swine can be caused by atypical mycobacteria

A

T

100
Q

Mycobacteria in swine can be caused by M. bovis and produces localized lesions.

A

F

101
Q

M. tuberculosis is a common mycobacterium infection of pig

A

F

T??
Pigs are highly susceptible to M. Tuberculosis

102
Q

Mycobacteria are acid and alcohol fast bacteria

A

T

103
Q

Sawdust bedding can predispose pigs to infection by facultative pathogenic mycobacteria.

A

T

104
Q

Facultative pathogenic mycobacteria can cause generalized tuberculosis in pigs.

A

F

Localized lesions

105
Q

The habitat of pathogenic mycobacteria is the soil

A

F

106
Q

The habitat of facultative pathogenic mycobacteria is the soil

A

F

107
Q

Only cattle are susceptible to Mycobacterium bovis

A

F

108
Q

Some facultative pathogenic Mycobacteria can cause tuberculosis in cold blooded
animals

A

T