PQ 1 Flashcards

1
Q

What is the location of Histomonas meleagridis?

A

digestive tract, liver and cecum

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2
Q

Cryptosporidium- where does sporogony occur (options: inside/outside host)?

A

inside

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3
Q

What is the size of the oocyst of Cryptosporidium?

A

4 - 6um

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4
Q

Life cycle of Cryptosporidium?

A

Schizogony:
- Host ingest oocyst, woth 4 sporozoites.
- Sporozoites released in small intestine
- Attach (not penetrate) to microvilli.
- Multiply and form schizont -> division -> 8 merozoites
- One more round of schizogony.

Gametogony:
- Formation of micro and macrogamonts
- Gamestocyst form and fuse -> zygote

Sporogony:
- 2 types of oocyst are formed
- 80% develop into thick walled. Pass to the environment with feces.
- 20% develop into thin- walled oocyst and release their sporozoites in the
intestine representing the autoinfective life cycle form.

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5
Q

Life cycle of Sarcocystis

A

Schizogony: Intermediat host
- Ingestion and excystation of oocyte in GIT (isospora type)
- Penetrate to blood – sporocyte -> meront -> merozoite
- 1 st generations – artery eoithelium, 2 nd gen. capillary ep., 3 rd gen in circulating
lymphocytes
- Striated mucles – enclosed in cysts
- Merozoite -> metrozoite -> bradyzoites - infective

Gametogony: Final host
- Sarcocyst – bradyzoites liberated
- Differentiate into gametocyst in lamina propria
- Micro and macro gamete –Z oocyst (isospora type)

Sporogony: in lamina propria

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6
Q

Texas cattle fever caused by? (multiple choice answers)

A. Babesia
B. bovis
C. bigemina

A

A. Babesia

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7
Q

Describe the location of Balatidium coli?

A

Intestinal tract of arthropods and some vertebrates, mainly pigs and humans

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8
Q

Haemoproteus is a parasite of? (animals)

A

birds

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9
Q

Phylum of Trichomonads?

A

Sarcomastigophora

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10
Q

Position of small and large babesia in erythrocytes?

A

Large: merozoites located centrally (larger than the radius of the RBC).

Small:
located in the periphery of the cell (smaller than radius of RBC)

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11
Q

Pathology of Giardia
Attachment of trophozoite causes: (4)

A
  1. Shortening of villi
  2. inflammation of crypts and lamina propria,
  3. lesions of mucosal cells.
  4. Malabsorption syndrome (steatorrhea)
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12
Q

What is the pathology of Cryptosporidium? How is it diagnosed?

A
  • Watery acute diarrhea, serious in young
  • Diagnosis: finding thick walled oocyst by fecal sample. Carbon fuchsin
    staining. Scrapings from trachea of birds. ELISA. Abs.
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13
Q

Pathology of toxoplasma?

A

Trophozoites directly destroy host cells, especially parenchymal and
reticuloendothelial cells. Lymph node infection, local hypersensitivity, blood vessel
blockage, abortions, stillbirth, chorioretinitis, hydroceohalus

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14
Q

Pathology of Histomonas, what are its lesions?

A

Lesions in cecum and liver, perforation in cecum and liver, large inflamated cecum,
yellow diarrhea, droopiness, black head
1. Invasive stage
2. Vegetative stage
3. Resistant stage
4. Flagellated stage

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15
Q

What are the important coccidian of poultry? Pathogenesis, clin. Signs, treatment?

A

Chicken:
- E.maxima – S.I
- E.tenello

Turkey:
- E.galloparones
- E.meleagrimitis
- E. adenoeidea

Goose:
- E.truncata
- E. anseris

Pathogenesis & clinical signs:
Destroys ep. Hemorrhage and malabsorption. Decreased production and weight
gain. Death.

Treatment:
Coccidiostats, vaccination, sanitation

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16
Q

Life cycle: Entamoeba

A
  • Ingestion of cyst -> excystation of ameba in small intestine
  • Nucleare divition (4->8), cytoplasm -> 8 small amebalae
  • Grow into trophozoites -> intestine, other organs.
  • 2 forms can develop:
  1. Forma minuta – Cronic, latent, 8-20um -> environment as cyst, encyctation
    in lumen, 4 nuclei
  2. Forma magna – (10 – 60um), invasive, dysenteric (no cysts), necrosis, flask
    shape ulcers – perforare GIT -> peritonitis – smeboma, abcess, 2 nd infection
17
Q

Trypanosoma brucei is transmitted by:

A. tsetse fly - Glossna spp.
B. Mechanically
C. Mosquitoes

A

A. tsetse fly - Glossna spp.

18
Q

Acute sleeping sickness is caused by:

a) T. ethansi
b) T. gambiensis
c) T. rhodesiensis

A

c) T. rhodesiensis

19
Q

Leishmania tropica causes:

A. Cutaneous
B. Visceral
C. Muco cutaneous form

A

A. Cutaneous

20
Q

What is the life cycle of Leishmania?

A

Insect: Vector (Phlebotomus / Lutzomyia)
- Promastigote in insect – lepomonad form
- To blood – phagocytosis by macrophages
- Amastigotes multiply by binary fission
- Macrophage rupture and release to blood – in reticulo epithelial cells

21
Q

Giardia intestinalis belongs to:

A. Apicomplexa
B. Diplomonadida
C. Microspora

A

B. Diplomonadida

22
Q

Cryptosporidium baileyi occurs in:
A. Calves
B. Piglets
C. Poultry

A

C. Poultry

23
Q

What size is the oocyst of Toxoplasma gondii?

A

12um

24
Q

Gametogony of T. gondii occurs in the small intestine of:

A. Rodents
B. Birds
C. Carnivores (felidae)

A

C. Carnivores (felidae)

25
Q

How is a human infected by toxoplasma?

A
  • Ingestion of sporulated oocysts (cat feces)
  • Ingestion of zoites (undercooked meat)
  • Congenital infection (only during acute stage)
  • Organ transplants
    o Chronic infection in donor
    o Immunosuppression
  • Blood transfusions (only during acute stage)
26
Q
A