PPS Obesity Outcomes Flashcards
What is obesity
Accumulation of fat stores to an extent that compromises health
BMI formula
Weight kg/height metres squared
below 18.5 = underweight, 25 or above = overweight, 30 or above = obese
Problems with BMI
Doesn’t allow for difference in weight between muscle and fat
Doesn’t consider location of fat
Visceral (Abdominal) fat is most harmful
Inaccurate in different ethnic groups
Less accurate in elderly with lost muscle mass.
Waist circumference
Considers location of fat
Men: Low<94cm, high 94-102cm, very high >102cm
Women: low<80cm, high 80-88cm, very high >88cm
Doesn’t take account of skeletal size
waist:hip or waist:height ratios
Complex to assess, lacks reference data and standardised measurement protocols
BMI and risk of CVD
A high body-mass index was most predictive of death from cardiovascular disease, especially in men
Link between body weight and cancer
Meta-analysis 89 prospective studies:
- Overweight and obesity associated with increased risk of breast, colorectal, endometrial, kidney, and ovarian cancers
- Association between weight and oesophageal cancer in men only
- Mixed associations for pancreatic and prostate cancer
” pathways linking obesity and ill-health
DIRECT PATHWAY
Obesity directly impacts physiology
INDIRECT PATHWAY
Obesity associated with poo health behaviours which in turn impacts health (eg smoking, eating behaviour, alcohol consumption)
Emotional consequences of obesity
Body dissatisfaction
Lower self-esteem in community samples
Higher rates of depression at the higher grades of obesity
Obesity: discrimination and social exclusion
Educational access
- Lower college attendance
- Lower teacher ratings of ability for obese girls
- Bullying and teasing at school
Marriage and social position
- Less likely to get married
- Downward socioeconomic trajectory for obese women
Employment
- Employers less willing to take obese people as employees
- Obese employees earn less and are less likely to get a promotion
Social stereotyping
- Unattractive
- Weak-willed
Causes of obesity
Are genes related to obesity?
Predicted by parental obesity
- One obese parent – 40% chance
- Two parents – 80% chance
- Healthy BMI parents - 7% chance
Twin studies
-Obesity far more similar in identical twins reared apart than in non-identical twins reared together
Adoptee studies
- Adoptee’s weight far more strongly related biological parents
What theories explain genetic vulnerability?
- Metabolic theory
- Low resting metabolic rate is heritable and is associated with weight gain - Fat cell theory
- Cell number mainly genetically determined
- Severely obese have larger and more cells
- Can increase number of cells, especially in childhood - Appetite theory
- Leptin regulates appetite
- Lack of evidence to show that obese individuals produce less leptin
‘Obesogenic environment’ as a cause of obesity
Food environment and activity environment
Food environment Availability Cost Variety Portion sizes High energy density (kcal/g) High fat Low fibre (not filling) Food advertising
Activity environment High cost of activity Labour saving devices Sedentary travel Enjoyable sedentary pastimes High ambient temperatures
MArketing and costs
Junk food targeted to children- marketing dollars spend a lot on advertising junk food to children compared to barely anything for healthy food messages
Junk food is also cheaper per calories compared to fresh fruits and vegetables
Increased portion sizes sold in US
Higher density of fast food outlets, in deprived areas