PPP Flashcards
0
Q
Functions of PPP
A
Produces NADPH
Produces ribose-5-phosphate
Metabolic use of 5-carbon sugars
1
Q
What pathway is responsible for synthesis of nitric oxide
A
HMP shunt
2
Q
How many ATPs are used by the PPP?
A
None. No consumption or production of ATP
3
Q
Rate limiting enzyme in PPP
A
Glucose 6-P dehydrogenase (G6PD)
4
Q
Two phases of PPP
A
Oxidative phase (irreversible) Non-oxidative phase (reversible)
5
Q
Products of oxidative phase of PPP
A
NADPH (2)
Ribulose-5-P
6
Q
Enzyme in non-oxidative phase of PPP
A
Transketolase
- requires thiamine
7
Q
Co-factor for transketolases
A
Vitamin B1
8
Q
Enzyme and co-factor for used by reduced glutathione sequestering of harmful H2O2
A
Glutathione peroxidase
Co-factor: selenium