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GI > PPIs > Flashcards

PPIs Flashcards

1
Q

Examples of PPI

A

Omeprazole, esomeprazole, pantoprazole etc

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2
Q

Cautions of PPI

A

MC GOLF

Magnesium - measure this especially with drugs that cause hypomagnesemia e.g. digoxin

C - masks symptoms of cancer

G - Can cause GI infections and issues (C.diff, N+V etc)

O - Osteoarthritis

L - Lupus (MHRA warning)

F - Fractures

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3
Q

MHRA advice on PPIs

A
  • Risk of SCLE - lesions appear on the skin when exposed to sunlight. If possible, consider discontinuing
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4
Q

What PPI is safe in pregnancy

A

Omeprazole

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5
Q

What interaction should we watch out for with PPIs

A

Avoid CLOE

(clopidogrel and omeprazole/esomeprazole. Lowers efficacy of clopidogrel so use other PPIs with it

Methotrexate - omeprazole decreases metabolism of methotrexate

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GI (20 decks)

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