Potions, poisons and prescribing Flashcards
What’s a drug?
Official - A drug is a chemical substance of known structure (other than a nutrient or essential dietary ingredient) which, when administered, produces a biological effect
(Lay - Something introduced to the body that has a measurable effect)
What’s the BIOAVAILABILITY of a drug?
% that gets from the stomach into the blood in an active form
The proportion of pharmacologically active drug that reaches the systemic circulation following oral administration
What is THERAPEUTIC INDEX?
Ratio of the maximum tolerated dose before an adverse drug reaction occurs vs. the minimum effective therapeutic dose
What are the 4 stages of pharmacokinetics?
Absorption
Distribution
Metabolism
Excretion