Posterior Pituitary Flashcards
1
Q
What is the impact of hypokalemia, hypercalcemia and lithium in the behavior of the ADH on the kidney?
A
- ⬇️ ADH effectiveness on principal cells at CD
* nephrogenic diabetes insipidus
2
Q
How do you make differential diagnosis of nephrogenic vs central diabetes insipidus?
A
Following Water deprivation and give desmopreessin, plasma levels ADH
- central: improve urine Os, ADH ⬆️
- nephrogenic: not improve urine Osm, ADH ⬇️
3
Q
How do you expect the plasma and urinary osmolality in SIADH?
A
Urinary osmolality >100 (high) + hyponatremia ▶️ SIADH
4
Q
Cause of central pontine myelinolysis
A
Fast correction of Na with 3% hypertonic saline a chronically hyponatremia