POST TEST 1 Flashcards
Which among the following is true regarding the ABO blood group system:
a. ABO antibodies are mostly IgG in nature
b. ABO antigens are haptens in nature
c. ABO blood group is the most immunogenic
d. ABO is ISBT 004
ABO blood group is the most immunogenic
This gene is said to be absent in a Bombay phenotype:
a. H gene
b. ABO gene
c. Le gene
d. Z gene
H gene
This antibody is present in Bombay phenotype that is not seen in a type O individual.
a. Anti-AB
b. Anti-A1
c. Anti-H
d. Anti-A1B
Anti-H
Formation of the ABO antigen on the red cell is controlled by what gene?
a. Se gene
b. H gene
c. Both
d. Neither
H gene
Formation of the ABO antigens on secretions is indirectly controlled by what gene?
a. Se gene
b. H gene
c. Both
d. Neither
Both Se and H gene
The type of antibody that is against an antigen found on the own patient red cells
a. Autoantibody
b. Alloantibody
c. Both
d. Neither
Autoantibody
What blood group would resemble
Bombay phenotype?
a. O
b. AB
c. A
d. NOTA
O
Which of the following lectins differentiates A1 from A2 cells?
a. Dolichos biflorus
b. Glycine soya
c. Salvia sclarea
d. Ulex europaeus
Dolichos biflorus
Anti H lectin would agglutinate which type of red blood cell:
a. A cell
b. B cell
c. O cell
d. AOTA
All A, B, O
Blood type of patient with negative agglutination on reverse typing of A cell, B cell, and O cells:
a. Type A
b. Type B
c. Type AB
d. Type O
Type AB
AHG is used to detect what type of antibody:
a. Warm reacting antibody
b. IgG
c. IgD
d. Both a and b
e. Both b and c
Both a and b
Reagent added to counter check the result of Coombs test:
a. Anti-H
b. Group O IgM coated RBCs
c. Group O IgG coated RBCs
d. NOTA
Group O IgG coated RBCs
The following disease may cause a positive reaction to DAT except:
a. Lead poisoning
b. Infectious mononucleosis
c. Infectious hepatitis
d. Chronic granulomatous disease
Chronic granulomatous disease
Direct antihuman globulin test is used to diagnose:
a. HDN
b. HTR
c. Autoimmune hemolytic anemia
d. AOTA
AOTA
It is the reason why blood group O is used as reagent check cells in Coombs test
a. Presence of expected antibodies
b. Absence of A and B antigens
c. It has more H antigens
d. None of the above
Absence of A and B antigens
Reaction medium used in antihuman globulin test which removes water in order to concen..
a. Albumin
b. DTT
c. Polyethylene glycol
d. LISS
Polyethylene glycol
To validate the reaction obtained in the antiglobulin test, one can:
a. Use green antiglobulin reagent
b. Add IgG-coated red cells to each test tube
c. Add IgG-coated red cells to each positive reaction
d. Add IgG-coated red cells to each negative reaction
Add IgG-coated red cells to each negative reaction
Type of immunoglobulin which is best in complement activation?
a. IgG
b. IgM
c. IgD
d. IgA
IgM
Which of the following IgG subclass is not capable of complement activation?
a. IgG1
b. IgG2
c. IgG3
d. IgG4
IgG4
The pentameric structure of IgM can be reduced into 5 monomers by the use of this agent
a. Thiol
b. DTT
c. Albumin
d. PEG
DTT
Testing for weakened expression of the D antigen is done by:
a. Enzyme techniques in conjunction with an IgM anti-D
b. Performance of an IAT using IgG anti-D
c. Increasing the time for the incubation of the saline phase d. Don’t need to do it in blood bank
Performance of an IAT using IgG anti-D
The immunogenicity of the Rh antigens may be described from greatest to least:
a. D>C>E>c>e
b. C>D>C>E>e
c. D>c>E>e>C
d. D>c>E>C>e
D>c>E>C>e
Individuals who do not have the Rh(D) factor are classified as:
a. Rh null
b. Du
c. Rh (-)
d. Rh (+)
Rh (-)
A patient’s red cells are typed as follows: Anti-D=4+; Anti-C=0; Anti-E=0. Which of the following got these results?
a. R2r
b. R1R2
c. R1r
d. R0R0
R0R0
These are solutions used to increase the degree of sensitization at 37 C incubation phase:
a. Enhancement media
b. Potentiators
c. Either A or B
d. Neither A nor B
Either A or B
