LONG TEST Flashcards
Testing for weakened expression of the D antigen is done by:
a. Enzyme techniques, in conjunction with an IgM anti-D
b. Performance of an IAT using an IgG anti-D
c. Increasing the time for the incubation of the saline phase d. Don’t need to do it in a blood bank
Performance of an IAT using an IgG anti-D
The immunogenicity of the common Rh antigens may be described from greatest to least:
a. D>C>E>c>e
b. c>D>C>E>e
c. D>c>E>e>C
d. D>c>E>C>e
D>c>E>C>e
Individuals who do not have the Rh(D) factor are classified as:
a. Rh null
b. Du
c. Rh (-)
d. Rh (+)
Rh (-)
A patient’s red cells are typed as follows: Anti-D=4+; Anti-C=0; Anti-E=0 Which of the following genotypes would correspond to these results?
a. R2r
b. R1R2
c. R1r
d. R0R0
R0R0
These are solutions used to increase the degree of sensitization at 37 C incubation phase:
a. Enhancement media
b. Potentiators
c. Either A or B
d. Neither A nor B
Either A or B
Which of the following genotype may demonstrate position effect.
a. DcE/DCE
b. DCE/DcE
c. Dce/Dce
d. DCe/Dce
DcE/DCE
Which of the following indicates for the absence of an antigen:
a. C
b. c
c. d
d. E
e. e
d
Maternal IgG antibody can remain in the circulation of the newborn and continually destroy the RBCs for how long?
a. 6 days
b. 24 hours
c. 7 days
d. 25 days
25 days
Rh HDFN demonstrates what type of hemolysis?
a. Intravascular hemolysis
b. Extravascular hemolysis
c. Either a or b
d. Neither a nor b
Intravascular hemolysis
Antibody considered as the most clinically significant next to Rh antibodies.
a. Anti Jka
b. Anti I
c. Anti-Kell
d. Anti-i
Anti-Kell
Which of the following IgG subclass can severely cause HDFN?
a. IgG1
b. IgG2
c. IgG3
d. IgG4
e. Both A and C
f. Both A and B
Both A and C
Rh null individuals would demonstrate depression of the following antigens, EXCEPT:
a. Ss
b. MN
c. U
d. All of the above
e. None of the above
All of the above
Which of the following Theories is not accepted in the Rh blood group:
a. Wiener
b. Fisher-Race
c. Molecular studies
d. A and B
e. B and C
Molecular studies
Which of the following condition cannot be transfused with Rh positive blood:
a. C in trans to RHD
b. Del
c. Partial D
d. Weak D
Partial D
f antigen is present if these compound antigens are also present:
a. CE
b. Ce
c. ce
d. rhi
e. None of the above
ce
Convert Dce/DCE to rosenfield:
a. Rh:1, 2,3,4,5
b. Rh:1,2,-3,4,5
c. Rh:1,2,3,-4,5
d. Rh:1,-2,-3,4,5
Rh:1, 2,3,4,5
Which of the following cases will demonstrate HDFN:
a. Rh (-) mother and Rh (+) fetus
b. Rh (+) mother and Rh (-) fetus
c. Rh (+) mother and Rh (+) fetus
d. Rh (-) mother and Rh (-) fetus e. None of the above
Rh (-) mother and Rh (+) fetus
Which of the following genotype of parents will give rise to an Rh negative offspring:
a. Dd, DD
b. DD, DD
c. Dd, Dd
d. Dd,dd
e. A and B
f. C and D
C and D
Which of the following genes is/are responsible for the expression of D,C,E,c,e:
a. RHD
b. RHCE
c. RHAG
d. All of the above
e. None of the above
All of the above
90.Which of the following RH terminologies has no genetic basis:
a. ISBT
b. Rosenfield
c. Fisher-race
d. Wiener
e. A and B
f. C and D
A and B
IgG coated RBCs in vivo are destroyed by what organ?
a. Kidney
b. Spleen
c. Thymus
d. Lymph nodes
Spleen
The antibody class implicated in hemolytic disease of the newborn.
a. IgM
b. IgG
c. IgD
d. IgE
IgG
Which of the following instance wherein Rhogam can be introduced to a patient:
a. 28th weeks of gestation
b. 72 hours after deliver
c. A and B
d. None of the above
A and B
An individual that is Rh (-) can elicit immune response by introducing D positive RBCs as little as:
a. 2 ml
b. 5ml
c. 1ml
d. .5 ml
e. None of the above
1 ml
Which of the following IgG subclass can severely cause HDFN?
a. IgG1
b. IgG2
c. IgG3
d. IgG4
e. Both A and C
f. Both A and B
Both A and C
Blood testused to measure the amount of fetal hemoglobintransferred from afetusto a mother’sbloodstream.
a. Rosette test
b. Kleihauer-Betke acid elution test
c. Cord blood sampling
d. None
Kleihauer-Betke acid elution test
Test that demonstrate D positive RBC of fetus, suspended in D negative suspension.
a. Kleihauer-Betke test
b. Rosette test
c. Rh typing
d. Weak D testing
Rosette test
A 36 year old woman is pregnant for the second time and prenatal testing shows the following result Rh(-), blood type A, IAT(-). Husband tested as Rh (-).
a. Candidate for RhIg
b. No need for RhIg
c. Low dose of RhIg should be given
d. Either A or B
No need for RhIg
In Kleihauer-Betke acid elution test, 50 fetal cells are counted in _____ adult cells.
a. 1,500
b. 200
c. 2000
d. 20
2000
Effect of having a bilirubin level of 18-20 mg/dL will lead to what specific condition in a fetus:
a. Hepatosplenomegaly
b. Kernicterus
c. Splenomegaly
d. None of the above
Kernicterus
