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Pharma 2 > Possible Short Q's > Flashcards

Possible Short Q's Flashcards

1
Q 
The oral bioavailability of aminoglycosides (except apromycin)?
A: 60-70%
B: 0-10%
C: 30-40%
D:90-100%
A

B: 0-10%

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2
Q 
Mode of action of Lincosamides
A: Detergent like activity 
B: Time dependent bactericidal 
C: Bacteriostatic
D: Conc dependent bactericidal
A

C: Bacteriostatic

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3
Q 
The primary choice of antibiotic for the treatment of swine erysipelas?
A: Enroflaxacin
B: Gentamycin
C: Penicillin
D: Doxycycline
A

C: Penicillin

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4
Q

Most effective in the treatment of chemotherapeutic induced vomitting, but less effective in other cases

A

Ondansetron

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5
Q

The most important toxological property of gentamicin?

A

Nephro and ototoxic

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6
Q

Primary choice of antibiotics used in the case of Rickettsia?

A

Tetracyclines

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7
Q

This macrolide antibiotic can only be administered SC in cattle?

A

Tilmicosin

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8
Q

The most frequently applied drug administered in combination with spectinomycin?

A

Lincomycin

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9
Q

The most active drug against rhodococcus equi infection in horses?

A

Erythromycin

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10
Q

When anthrax is diagnosed in domestic animals which drug should you administer?

A

Penicillin

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11
Q

Among the listed antibiotics, which would you choose for the treatment of bite wounds?

A

Amoxicillin and Clavulanic acid

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12
Q

Streptomycin is usually combined with this antibiotic?

A

Procaine and benzathine penicillin

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13
Q

This antibiotic is active against fungi, and can be applied orally

A

Griseofulvin

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14
Q 
Which drug is most effective against Bordetella bronchiseptica from the following?
Bacitracin
Doxycycline
Penethamat
Cefalexine
A

Doxycycline

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15
Q 
This drug can be used in foals for the treatment of R.equi infection?
Tulathromycin
Doxycycline
Clindamycin
Erythromycin
A

Erythromycin

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16
Q 
Which substance can be used intramammarily against penicillinase producing s.aureus?
Cloxacillin
Benzathine-penicillin
Procaine-penicillin
Penethamat
A

Cloxacillin

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17
Q

Long acting cephalosporin for the treatment of dogs and cats

a. Cepharin
b. Cefazolin
c. Cefalexin
d. Cefovecin

A

d. Cefovecin

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18
Q

In the case of coli- septicaemia in swine, which drug would you apply in medicated water?

a. Gentamicin
b. Lincomycin
c. Enrofloxacin
d. Tylosine

A

c. Enrofloaxacin

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19
Q

Among the listed agents this one is NOT intended against infections caused by anaerobic bacteria

a. Trimethoprim
b. Pradofloxacin
c. Metronidazole
d. Clindamycin

A

a. Trimethoprim

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20
Q

In the case of fowl cholera ( Septicaeima) in chickens, which of the following antibiotics would you apply in medicated water?

a. Gentamicin
b. Amoxicillin
c. Colistin
d. Neomycin

A

b. Amoxicillin

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21
Q

Frequent combined partners of dihidro-streptomycin

a. Procain- and benzathine penicillin
b. Amoxicillin and clavulanic acid
c. Oxacilllin and cloxacillin
d. Cefapirin and cefazolin

A

a. Procaine and benzathine penicillin

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22
Q

This drug ( group) is usually incompatible with tiamulin and the macrolide antibiotics:

a. Amprolium
b. Triazine anticoccidials
c. Ionophor antibiotics
d. Halofuginone

A

c. ionophor antibiotics

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23
Q

This macrolide reaches high concentration in bronchial fluid, and persists for a long time:

a. Tylosin
b. Josamycin
c. Tulathromycin
d. Erytrhomycin

A

c. Tulathromycin

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24
Q

This antibiotic can penetrate well intracellularly

A

Oxytetracycline

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25
Q

Combined with cephalosporins the nephrotoxic effect of this drug can be enhanced

A

Gentamicin

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26
Q

Important indication for the use of tetracyclines:

a. treatment of intestinal infections
b. Tuberculosis
c. Metritis, foot rotting, local treatment of wounds
d. Swine- dysentery

A

c. Metritis, foot rotting, local treatment of wounds

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27
Q

Aminocyclitol, its mode of action is bacteriostatic:

a. Streptomycin
b. Gentamicin
c. Spectinomycin
d. Neomycin

A

c. spectinomycin

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28
Q

Organisms resistant to the macrolides

a. most of the gram- positive organisms
b. E. coli and Salmonella ssp.
c. Mycoplasmae
d. fastidious gram- negative organisms

A

b. E.coli and salmonella sp

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29
Q

Which of the following antibiotics would you apply in an animal with severe renal impairment?

a. Doxycycline
b. Gentamicin
c. Tobramycin
d. Enrofloxacin

A

d. Enrofloxacin

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30
Q

Antibacterial drug with bactericidal mode of action:

a. Erythromycin
b. Spectinomycin
c. Lincomycin
d. Gentamicin

A

d. Gentamicin

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31
Q 
Administration of this drug to herbivorous rodents in NOT recommended because of the risk of dysbacteriosis: 
A) Enrofloxacin 
B) Lincomycin
C) Spectinomycin
D) Sulfadimidine
A

B) Lincomycin

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32
Q 
This drug has severely harmful effect on the intestinal flora: 
A) Clindamycin
B) Sulfamethoxasole + TMP
C) Enrofloxacin
D) Bacampicillin
A

C) Enrofloxacin

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33
Q

Antibacterial drug with bactericidal mode of action:

a. Erythromycin
b. Spectinomycin
c. Lincomycin
d. Gentamicin

A

d. gentamicin

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34
Q

Cephalosporin against mycoplasma

A

NONE!!!!

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35
Q

What bacteria are susceptible to macrolides?

A

Mycoplasma and brachyspira hyodysentery

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36
Q

Least toxic aminoglycoside

A

Spectinomycin

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37
Q

What drug would you use in a urinary tract infection?

A

Gentamycin

38
Q

What drug would you use in renal failure?

A

Cephalosporins (cetoperazone, cettriaxone, cefador)

39
Q

What causes haemorrhagic syndrome in chicken?

A

Sulphaquinoxaline, sulphonamides, virus

40
Q

Doxycyline is used against what disease?

A

Lyme Dx

41
Q

What can cause Dysbacteriosis in rodents?

A

Lincomycin, penicillin, tetracycline, macrolides

42
Q

Gentamicin is not effective if administered?

A

PO

43
Q

Which antibiotic is toxic to herbivore rodents?

A

Lincomycin

44
Q

What drug is used in the treatment of Swine Dysentery?

A

Tylvalosin, Lincomycin, Tiamulin, Tylasin

45
Q

What antibiotic causes yellow discolouration in puppies?

A

Oxytetracyclines

46
Q

What drug is not suitable for lower urinary tract infection?

A

Penicillins and cephalosporins

47
Q

What does tetracycline work against?

A

Rickettsia, Borrelia, Mycoplasma, Chlamydia

48
Q

Which drug can be used against swine dysentery both PO and IV?

A

Thiamulin

49
Q

What drug is not suitable for herbivore/rodents?

A

Lincomycin, macrolides, tql

50
Q

What is normally contraindicated with Tiamulin?

A

Ionophore antibiotics

51
Q

Aminoglycoside used in P.aeruginosa?

A

gentamicin

52
Q

4th generation cephalosporin?

A

Cefquinone

53
Q

Which penicillin administered IM has long DOA?

A

Penicillin benzathine

54
Q

Swine salmonella E.coli enteritis?

A

Apramycin

55
Q

Polipeptide antibiotic, when it is applied in injection can be highly neuro- and nephrotoxic:

A

Colistin sulphate

56
Q

Appropriate for the treatment of enteritis caused by E.coli and Salmonellae:

A

Gentamicin

57
Q

This antibiotic can be used for the treatment of mastitis caused by penicillinase producing Staphylococcus aureus:

A

Oxacillin

58
Q

Among the listed macrolides this one has cardiotoxic effect (e.g. in goats):

A

Tilmicosin

59
Q

Which is characteristic to polypeptide antibiotics?

A

They have bactericidal effect

60
Q

Which bacterium is highly sensitive to Cephalexine?

A

Staph.pseudointermedius

61
Q

This antibiotic has very short lasting effect, it has to be applied IV approx. 6 times a day:

A

Benzylpenicillin-Na

62
Q

Among the listed Aminoglycosides this agent is active against Pseudomonas aeruginosa:

A

Amikacin

63
Q

Procaine-benzylpenicillin is ineffective against:

A

E.coli

64
Q

First generation Cephalosporins, it cannot be applied orally, in veterinary medicine frequently used in intramammary infusions:

A

Cefapirin

65
Q

Aminoglycoside that is active against Mycoplasma:

A

Spectinomycin

66
Q

This Macrolide is NOT intended for the treatment of young foals:

A

Tylosin

67
Q

This penicillin antibiotic has long acting effect applied IM:

A

Benzathine penicillin

68
Q

Which of the following is the least toxic aminoglycoside?

A

Spectinomycin

69
Q

The antibiotics in this groups bound to the 30s subunit of the bacterial ribosome they interact with protein synthesis:

A

Aminoglycosides

70
Q

This antibiotic inhibits the cell wall synthesis of bacteria, due to its high nephrotoxicity it is used only topically or orally:

A

Bacitracin Zn

71
Q

Antibacterial drug with bactericidal mode of action

A

Gentamicin

72
Q

Administration of this drug to herbivorous rodents is NOT recommended because of the risk of dysbacteriosis?
A. Sulfadimidine
B. Spectinomycin
C. Enrofloxacin D. Lincomycin

A

Lincomycin

73
Q

Administration of this drug to herbivorous rodents is NOT recommended because of the risk of dysbacteriosis?
A. Gentamicin
B. Clindamycin
C. Sulfamethoxasole D. Enrofloxacin

A

Clindamycin

74
Q 
Not bactericidal antibiotic: 
A. Doxycycline
B. Gentamicin
C. Amoxicillin
D. Enrofloxacin
A

A. Doxycyline

75
Q 
Not bactericidal antibiotic:
A. Ampicillin
B. Marbofloxacin
C. Erythromycin
D. Neomycin
A

C. Erythromycin

76
Q 
Its absorption after oral administration is very limited thus it is a good choice for the treatment of enteric infections given orally:
A. Neomycin
B. Amoxicillin
C. Enrofloxacin
D. Sulfamethoxasole
A

A. Neomycin

77
Q

In case of risk septicemia in swine which drug would you apply in medicated water

A

Enrofloaxacin

78
Q

Hypocalcaemia can occur with the IV administration of this antibiotic:

A

Oxytetracycline

79
Q

The aminoglycosides are accumulated in this organ thus their withdrawal period is long: A. Spleen
B. Liver
C. Pectoralmuscle
D. Kidney

A

D. Kidney

80
Q 
Among the listed Macrolides following a single application this one has high concentration and long action (6-8 days) in bronchial fluid:
A. Azithromycin
B. Tylosin
C. Erythromycin
D. Tulathromycin
A

D. Tulathromycin

81
Q 
The antibiotics in this group inhibit the cell wall synthesis of bacteria and they are active against E.coli:
A. Polymixins
B. Narrow spectrum penicillins
C. Aminopenicillins 
D. Aminoglycosides
A

C. Aminopenicillins

82
Q 
Which of the below mentioned organisms are susceptible to the tetracyclines?
A. Mycoplasmae,Borreliae,Rickettsiae
B. Chlamydiae,Coccidiae
C. Mycobacteria,Mycoplasmae
D. Coccidia,Pseudomonas
A

A. Mycoplasmae, Borrelia, Rickettsiae

83
Q 
This substance is not used on its own because of the low achieved plasma concentrations 
A. Benzathine-penicillin
B. Procaine-penicillin
C. Amoxicillin
D. Benzylpenicillin
A

A. Benzathine penicillin

84
Q

Which is characteristic to polypeptide antibiotics?

A

They have bactericidal effect

85
Q

This aminoglycoside is not used on its own (alone) because of the widespread resistance:

A

Streptomycin

86
Q

First Generation Cephalosporin, it is applied orally and parenterally as well:

A

Cephalexin

87
Q 
Which ß lactam acts against chlamidophila? 
A. None of these
B. Cefquinom
C. Amoxicillin-clavulanicacid
D. Piperacillin-tazobactam
A

A. None of these

88
Q 
Aminoglycoside that is active against mycoplasma: 
A. Streptomycin
B. Spectinomycin
C. Neomycin
D. Lincomycin
A

B. Spectinomycin

89
Q 
Among the listed agents this one is the most effective against Brachyspirahyodysenteriae: 
A. Doxycycline
B. Tiamulin
C. Erythromycin
D. Tylosin
A

B. Tiamulin

90
Q

The most effective macrolide for the treatment of swine dysentery:

A

Tylvalosin

Pharma 2 (6 decks)

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