Drug names MT 2 Flashcards

1
Q

Most important cell wall inhibitors

A

Beta-lactams (penicillins and cephalosporins)
Glycopeptides
Bacitracin

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2
Q

Ergosterol synthesis inhibitors:

A

The Azoles!!
Ketoconazole
Itraconazole
Miconazole

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3
Q

Ergosterol complex formers:

A

Polienes!

Amphotericin-B

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4
Q

Dihydrofolate reductase inhibitors:

A

Trimethoprim

Methotrexate

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5
Q

Antineoplastic drugs

A

Antimetabolites! e.g 5-fluorouracil

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6
Q

Antiparasitic drugs

A

Levamisole

Pyrantel

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7
Q

Category A drug:

A

Vancomycin against MRSA infections (life-threatening)

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8
Q

Category B drugs:

A

Fluoroquinolones
3-4 generation cephalosporins
Colistin

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9
Q

Bactericidal Drugs

A
Penicillins 
Cephalosporins 
Aminoglycosides
Polypeptides
Potentiated SA
Fluoroquinolones
Metronidazole
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10
Q

Bacteriostatic

A
Tetracyclines 
Macrolides
Lincosamides
Pleuromutilins 
Phenicols
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11
Q

Synergestic drugs

A

Penicillin and streptomycin

Lincomycin (50S) and spectinomycin (30S)

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12
Q

Additive Drugs

A

Gentamicin (aerobic) and Metronidazole (anaerobic)

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13
Q

Antagonists

A

Erythromycin and Chloramphenicol

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14
Q

The beta-lactam antibiotics:

A
Penicillins 
Cephalosporins 
Lactamase inhibitors
Monobactams 
Carbapenems
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15
Q

Agents targeting the cell wall

A

Bacitracin
Vancomycin
Beta-Lactams

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16
Q

Beta Lactamase inhibitors

A

Clavulinic acid (+amoxicillin)
Sulbactam (+ampicillin)
Tazobactam (+piperacilin)

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17
Q

Narrow spectrum penicillins

A

Benzylpenicillin Na,K
Benzylpenicillin Procaine
Benzylpenicillin Benzathine
Phenoxymethyl Penicillin

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18
Q

Penicillinase stable penicillins

A
Acid sensitive: Methicillin
Acid Resistant: 
Oxacillin
Cloxacillin
Dicloxacillin
Flucloxacillin
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19
Q

Broad spectrum penicillins

A

Ampicillin
Amoxicillin
Basampicillin
Pivampicillin

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20
Q

Penicillins against pseudomonas

A

Carbox-penicillins:
Carbenicillin
Ticarcillin

Ureidopenicillins:
Piperacillin
Tazobactam

21
Q

Gen 1 Cephalosporins:

A
Oral: Cephalexin
Parenteral:
Cephapirin
Cefacetril
Cephazoline
Cefadroxil
22
Q

Gen 3 Cephalosporins:

A
Parenteral: 
Cefoperazon
Ceftazidim
Ceftiofur
Cefovecin
Ceftriaxone 
Cefotaxime
23
Q

Gen 4 Cephalosporins

A

Cefquinone

24
Q

Monobactams

A

Aztreonam

Trigemonam

25
Q

Carbapenems

A

Imiperem

Meropenem

26
Q

Aminoglycosides

A
Streptomycin/ Dihydrostreptomycin
Neomycin
Gentamicin
Spectinomycin
Apramycin
Tobramycin
Amikacin
27
Q

Aminocglycosides produced by streptomyces spp

A
Streptomycin
Neomycin
Spectinomycin
Kanamycin--- Amikacin
Tobramycin
28
Q

Aminoglycosides produced by micromonospora spp

A

Gentamicin

29
Q

Inhibitors of protein synthesis 30S ribosome subunit

A

Aminoglycosides

Tetracyclines

30
Q

Inhibitors of protein synthesis 50S ribosome subunit

A

Macrolides
Lincosamides
Pleuromutilins
Phenicols

31
Q

Short Acting TTC’s

A

Tetracycline
Oxytetracycline
Chlortetracycline

32
Q

Intermediate acting TTC’s

A

Demeclocycline

33
Q

Long acting TTC’s

A

Doxycycline

Minocycline

34
Q

Name the most important macrolides

A
Erythromycin
Tylosin
Tilmicosin
Clarithromycin
Azithromycin
35
Q

Name the macrolide macrolides

A
Erythromycin
Tylosin
Spiramycin
Tilmicosin
Tylvalosin
Tildipirosin
Clarithromycin
Roxithromycin
36
Q

Name the azalide macrolides

A

Gamithromycin

Azithromycin

37
Q

Name the triamilide macrolides

A

Tulathromycin

38
Q

Name the Phenicols

A

Chloramphenicol
Tiamphenicol
Florfenicol

39
Q

Name the Lincosamides

A

Lincomycin

Clindamycin

40
Q

Name the Pleuromutilins

A

Tiamulin

Valnemulin

41
Q

First gen Glycopeptides

A

Vancomycin
Teicoplanin
Ramoplanin

42
Q

Second gen (semi-synth) Glycopeptides

A

Oritavancin
Dalbavancin
Telavancin

43
Q

Name the Rifamycins

A

Rifampicin/Rifampin

Rifabutin

44
Q

Name the Polymyxins

A

Polymyxin B,E and Colistine

Muciproin

45
Q

Local sulphonamides

A

Sulfacetamide
Mafenide
Silver sulfadiazine
Sulfathiazine

46
Q

Intestinal disinfectant sulphonamide

A

Sulfaguanidine

47
Q

Systemic, short-acting sulphonamides

A
Sulfadimidine 
Sulfachlorpyridazine 
Sulfadoxine 
Sulfadiazine 
Sulfamethoxasole 
Sulfaquinoxaline 
Sulfachlorpyrazine 
Sulfasalazine
48
Q

Systemic, long-acting sulphonamides

A

Sulfadimethoxine

Sulfamethoxypyrazine

49
Q

2,4 Diaminopyrimidines

A

Trimethoprim
Aditoprim
Ormethoprim
Baquilloprim