Drug names MT 2 Flashcards
Most important cell wall inhibitors
Beta-lactams (penicillins and cephalosporins)
Glycopeptides
Bacitracin
Ergosterol synthesis inhibitors:
The Azoles!!
Ketoconazole
Itraconazole
Miconazole
Ergosterol complex formers:
Polienes!
Amphotericin-B
Dihydrofolate reductase inhibitors:
Trimethoprim
Methotrexate
Antineoplastic drugs
Antimetabolites! e.g 5-fluorouracil
Antiparasitic drugs
Levamisole
Pyrantel
Category A drug:
Vancomycin against MRSA infections (life-threatening)
Category B drugs:
Fluoroquinolones
3-4 generation cephalosporins
Colistin
Bactericidal Drugs
Penicillins Cephalosporins Aminoglycosides Polypeptides Potentiated SA Fluoroquinolones Metronidazole
Bacteriostatic
Tetracyclines Macrolides Lincosamides Pleuromutilins Phenicols
Synergestic drugs
Penicillin and streptomycin
Lincomycin (50S) and spectinomycin (30S)
Additive Drugs
Gentamicin (aerobic) and Metronidazole (anaerobic)
Antagonists
Erythromycin and Chloramphenicol
The beta-lactam antibiotics:
Penicillins Cephalosporins Lactamase inhibitors Monobactams Carbapenems
Agents targeting the cell wall
Bacitracin
Vancomycin
Beta-Lactams
Beta Lactamase inhibitors
Clavulinic acid (+amoxicillin)
Sulbactam (+ampicillin)
Tazobactam (+piperacilin)
Narrow spectrum penicillins
Benzylpenicillin Na,K
Benzylpenicillin Procaine
Benzylpenicillin Benzathine
Phenoxymethyl Penicillin
Penicillinase stable penicillins
Acid sensitive: Methicillin Acid Resistant: Oxacillin Cloxacillin Dicloxacillin Flucloxacillin
Broad spectrum penicillins
Ampicillin
Amoxicillin
Basampicillin
Pivampicillin