Portal HTN Flashcards
portal vein normal pressure
5-8mmhg
Portal hypertension
> 10-12mmhg
Some of collaterals
Left renal v
Diaphragm
Retroperitoneum
V
Varices incidence
90% of cirrhotic
1/3 will bleed with 25%mortality
Specific managment of varices
Urgent Endoscopic (within 2-12h) therapy
1. Banding
2. Sclerotherapy
• IV vasoconstrictors
• TIPS
• Surgical shunting
Acute varices TTT oof choice
sclerotherapy and banding
Examples of vaso pressor
Terlipressin.
■ Somatostatin.
■ Octreotide.
Balloon tamponade CI
Severe hge
Can be left up to 12h
Emergency surger(last option)
TIPS
• Esophageal transection and ligation
Acute portosys shunt
Varices prevention
NON SELECTIVE B OR ALPHA AND BETA BLOCKER(CArvidelol)
1)Oral propranolol
(*decrease in cardiac output (B1),
*blockade of β2 vasodilator receptors on the
splanchnic A)1st line
2)Endoscopic ablation(Banding
Major risk of shunts
Encephalopathy
The ‘shunts’ performed are usually an end-to-
side portocaval anastomosis or a selective
distal splenorenal
Devascularization procedures including
esophageal transection
do not produce
encephalopathy
Intrahepatic portal HTN
Schistosomiasis
PBC
Post hepatic obstruction
IVC
VENO OCCLOSIVE
budd-chiari syndrome
PrehePatic obs
Portal vein thrombosis