NAFLD Flashcards
HEPATIC STEATOSIS
Diagnosis
imaging or biopsy with at least one cardiometabolic
RF
Cuases of hepatic steatosis
Alcohol:
• Hepatitis C
• TPN
• Short bowel syndrome
• Rapid weight ;oss
Most imp factor in mortality
Presence of fibrosis
Fatty liver diagnosis
Us(bright) ct MRI
Measure BMI
Exclude other causes of liver diseases
ASSESMENT OF FIBROSIS
BIOBSY GS
1 TE (transient elastography)
2 MRE(magnetic resonance )
3 NFS
4 Fibrosure test
Indication for BIOBSY
high NAFLD fibrosis score (NFS or FIB-4).
high liver stiffness by TE or MRE
Mc CAUSE OF DEATH
MC cause of death in NAFLD
is CVS disease
Weight loss effectiveness
5% can improve
steatosis, 10% can reverse fibrosis
Drug managment
1 )resmitrom(thyroid agonist)
2) ins sens(Pioglitazone)
3)VIT E(for non diabetic)
800IU/d)