Population Genetics Flashcards

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1
Q

Define population genetics.

A

Describing, modelling and explaining changes in allele frequencies within and among populations.

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2
Q

Define evolution.

A

The change of allele frequencies in populations over time.

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3
Q

How can you infer migration using genetic similarity?

A

High genetic similarity suggests high dispersal or recent isolation. Low genetic similarity suggests low dispersal or long history of isolation.

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4
Q

What does a genetic divergence-geographical distance graph show?

A

It shows the barriers, vagility and duration of isolation.

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5
Q

What does a morphological divergence-genetic divergence graph show?

A

It shows the selective forces and how diversity arises.

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6
Q

What is the proximate cause?

A

Genes that have different alleles.

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7
Q

How many alleles can an individual have at each locus?

A

Up to 2.

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8
Q

How many alleles can be found in the genes of a population?

A

More than 2.

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9
Q

Define a gene pool.

A

The entirety of alleles at a given locus for a population.

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10
Q

What does the Hardy-Weinberg principle explain?

A

Which genotype frequencies to expect in the next generation if the genotype frequencies of the parental generation are known.

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11
Q

What are some of the assumptions in the Hardy-Weinberg principle?

A

1) Diploid organisms.
2) Sexual reproduction only.
3) Random mating.
4) Non-overlapping generations.
5) Infinitely large population.

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12
Q

Why is the Hardy-Weinberg principle still accurate when there are so many assumptions?

A

Because the assumptions tend to cancel each other out.

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13
Q

What is a polymorphic locus?

A

A locus with more than 1 allele in a population.

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14
Q

What is the effect on genotype of inbreeding?

A

An excess of homozygotes.

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15
Q

What is the effect on genotype of outbreeding?

A

A lack of homozygotes.

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16
Q

Define genetic drift.

A

Changes in allele frequency due to random effects.

17
Q

How does population size impact genetic drift?

A

Smaller populations are more greatly affected by genetic drift.

18
Q

What can frequency of heterozygous individuals be used to estimate?

A

To estimate genetic variability. More heterozygous individuals = more variability.

19
Q

How do you calculate expected heterozygosity (Hexp)?

A

Hexp = 2 p q

20
Q

How do you work out the number of pairwise combinations of all alleles, using n as the number of alleles?

A

n(n-1)/2

21
Q

Define nucleotide diversity.

A

The average % of nucleotides that differ between any randomly sampled pair of sequences.