Population Genetics

Question 1

study of distributions and changes of allele frequency and interaction of alleles in a population and b/t populations; deals with genetic and environmental factors

Answer 1

population genetics

Question 2

relative frequency of an allele at a particular locus in a population

Answer 2

allele frequency

Question 3

natural selection
genetic drift
mutations
gene flow

Answer 3

evolutionary forces

Question 4

equation for genotype at each locus

Answer 4

p+q=1

Question 5

equation for cumulative probability of all genotypes in the population

Answer 5

p^2 + 2pq + q^2=1

Question 6

if disease caused by recessive allele affects 0.01% of the population, how would you calculate recessive allele frequency

Answer 6

take the sq. root of the number after you switch it out of percentage

Question 7

determines if mutation/allele is eliminated, becomes stable, or becomes predominant

Answer 7

fitness (f)

Question 8

equation for selection

Answer 8

s=1-f

Question 9

for recessive diseases under selection, how do you determine frequency of alleles

Answer 9

2q^2

Question 10

create new alleles of genes; implies detrimental phenotype

Answer 10

mutations

Question 11

has no phenotype

Answer 11

polymorphism

Question 12

in a pedigree with dominant inheritance, the affected individual is almost always what

Answer 12

a heterozygote

Question 13

for x-linked recessive disorders, selection is limited to who

Answer 13

hemizygous males

Question 14

if the distance b/t locus 1 and locus 2 is very small, what happens to recombination

Answer 14

won’t happen

Question 15

frequency of a mutation equation for x-linked recessive disorders

Answer 15

mu= sq/3