Poll Questions Flashcards

(41 cards)

1
Q

Which best describes a “myofibril”?

A

It is a cylindrical cellular organelle
composed of myofilaments

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2
Q

What is the role of calcium in muscle contractions?

A

to bind with troponin, changing its shape so
the actin filament is exposed.

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3
Q

You have designed a drug that is supposed to bind to the myosin binding sites on actin. You inject it into a relaxed muscle, but find that none of the drug is bound. Why?

A

The myosin binding sites on actin are covered by
tropomyosin.

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4
Q

How is the length of a skeletal muscle cell related to the
force it can generate?

A

Skeletal muscle cells generate the most force when the
contraction occurs at an intermediate length

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5
Q

What would be the result if the administration of a
drug sequesters (inactivates) all the ATP in a
cell?

A

All cross-bridges will remain tightly bound to
actin

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6
Q

The major physiological difference between single-unit
smooth muscle and multi-unit smooth muscle is

A

Action potentials can spread from cell to cell in single-
unit, but not in a multi-unit muscle.

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7
Q

Which group of chemicals does
NOT contain hormones?

A

Carbohydrates

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8
Q

The specific action of hormones is due to:

A

hormone-specific receptors in target cells

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9
Q

When a certain gland extract gland is applied to
some cells, these cells respond by starting cell
division. However, when a c-AMP inhibitor is first
applied to the cell and then the gland extract is
applied, the cells do not divide.
Therefore, the gland extract most likely contains

A

a peptide hormone

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10
Q

The anterior pituitary gland releases all of
the following hormones

A

follicle-stimulating hormone (FSH).
thyroid stimulating hormone (TSH).
prolactin.
growth hormone (GH)

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11
Q

What controls the release of corticoids
from the adrenal cortex?

A

Higher brain centers
CRH from the hypothalamus
ACTH from the anterior pituitary

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12
Q

Which of these pituitary hormones is not
released in response to a releasing hormone
from the hypothalamus?

A

ADH
Insulin

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13
Q

Which of these is true of the adrenal medulla?

A

It functions as part of the sympathetic nervous
system

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14
Q

The mode of action of insulin is by

A

adding GLUT-4 transporters to muscle and fat
cells
stimulating phosphorylation of intracellular
glucose in liver cells.

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15
Q

Blood samples from an individual who has fasted
(not eaten) for 24 hours would have:

A

high levels of glucagon and low levels of insulin.

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16
Q

he hormone ____ is a modified amino
acid, whereas ____ is a steroidal hormone.

A

epinephrine, testosterone

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17
Q

George’s symptoms
1. Frequent urination: polyuria.
2. Increased thirst: polydipsia.
3. Increased appetite: polyphagia.
Are George’s symptoms consistent with
type 1 DM, type 2 DM, both, or neither?type 1 DM, type 2 DM, both, or neither?

18
Q

Where is the Atrial repolarization?

A

Hidden in QRS complex.

19
Q

In vertebrate heart, many pacemaker cells
(myogenic cells) in SA node, each with their
own spontaneous AP firing rate.
If they all start firing at the same time, which
pacemaker cell determines the basic heart
beat frequency?

A

Cell with fastest AP frequency

20
Q

In vertebrate heart, many pacemaker cells
(myogenic cells) in SA node, each with their own
spontaneous AP firing rate.
What happens to the heart beat frequency if
this pacemaker cell dies? Which cell
determines basic heart rate frequency?

A

Cell with next fastest AP frequency

21
Q

If the stroke volume is 80 ml and the
heart rate is 70 beats per minute, the
cardiac output is

A

5600 ml/min
CO = HR X SV

22
Q

Through which vessel is the velocity
of blood flow the slowest?

23
Q

Which of the following statements concerning the
capillaries is FALSE?

A

Increasing capillary hydrostatic pressure decreases
the likelihood that filtration will occur.

24
Q

The affinity of hemoglobin for oxygen is
____ if PO2 is low and is ____ if PO2 is high.

25
The Bohr effect describes the ________
effect of pH on the affinity of hemoglobin for oxygen
26
For maximum efficiency in loading oxygen at the lungs
the temperature should be slightly lower than normal body temperature
27
The ventilation/perfusion ratio ______
increases when blood flow is decreased
28
In muscle physiology, the correct technical meaning of “contraction” is:
b. the active state of a muscle, producing some combination of force or movement
29
The thick filament of a myofibril of a skeletal muscle contains a protein called
myosin
30
arrange this list of events in excitation-contraction coupling in the correct order
motor endplate depolarizes action potential travels over muscle cell membrane action potential travels down t-tubules Ca++ released through channels from SR Ca++ pumped into SR
31
The major functional difference between single-unit (visceral) smooth muscle and multi-unit smooth muscle is:
a. action potentials can spread from cell to cell in single-unit, but not in multi-unit
32
What will happen to the muscle contraction if ATP is unavailable?
d. The muscle becomes rigid due to failure of cross-bridges to detach from actin filaments.
33
A motor unit in muscles
d. includes all muscle fibers connected to one motor axon.
34
8. The energy used for muscle contractions after 30 minutes mostly comes from
Fatty acids
35
9. The difference between a muscle twitch and tetanus is due to
a. the duration of the active state of the muscle.
36
The primary role of calcium in the activation of smooth muscle is to
c. activate myosin molecules so they can interact with actin filaments
37
11. During an isometric muscle contraction the
c. series elastic components stretch
38
12. In regards to the relationship between resting muscle fiber length and tension generated, ________.
a. maximal tension is generated when the thick and thin filaments slightly overlap
39
Which muscle fiber type produces a high level of force-generation, a fast speed of contraction, and has a low level of oxgygen capacity?
c. Fast glycolytic
40
14. Myosin contains binding sites for ________ and ________.
c. ATP; actin
41
15. The T-tubules __________
provide a means of rapidly transmitting the AP from the surface into the central portions of the muscle fiber. d. contain the DHP-receptor.