Pleural Dz Flashcards
Pleura
Serous membrane
Viscerla pleura
covers the lungs and adjoining structures (blood vessels, bronchi, nerves)
Parietal Pleura
- attached to the chest wall
- covers the diaphragm
Pleural cavity
- Potential space between the two pleurae
- Allows smooth inhalation and exhalation, the fluid prevents friction
Costal pleura
Lines inner ribs
Diaphragmatic Pleura
lines diaphragm
Costodiaphragmatic Recesses
-Spaces between costal and diaphragmatic pleura
Pleuritis causes
Infection:
- Viral*
- Bacterial
- Fungal
Pleuritis clinical presentation
- SHARP CP- Aggravated by breathing, coughing, sneezing
- Fever, chills
- Cough
- SOB
* depends on underlying cause
Pleuritis PEx
Pleural friction rub
Pleuritis Treatment
- NSAIDS: Naproxen
- Steroids: Prednison-For refractory pain
- Proton Pump Inhibitor: Omeprazole- prophylactic tx of GI upset due to NSAIDS
What is often the presenting sx in Lupus pleuritis
Pleurisy!
Lupus pleuritis diagnostics
- Serologic testing for SLE: ANA, anti-dsDNA
Lupus pleuritis Tx
NSAIDS
Rheumatoid pleuritic common signs
- Pleuritic CP
- Fever
- +/- Dyspnea
Rheumatoid pleuritic causes
- Exudative “rheumatoid” effusion
- Drug-induced pleuritis: methotrexate, infliximab
- Empyema
- Bronchopleural fistula
- Hemopneumothorax
- Pyopneumothorax
What is the most common pleural dz?
Pleural effusion
What is pleural effusion a result of?
- Excess fluid production AND/OR
2. Decreased lymphatic absorption
What are the 4 major causes of pleural effusions
- Congestive heart failure
- Pneumonia
- Malignancy
- Pulmonary embolism
What are the two distinct categories of pleural effusions?
- Transudative effusions
2. Exudative effusions
Pleural effusion clinical presentation
- Dyspnea
- Cough
- Pleuritic chest pain
* Variability depending on underlying disease
Pleural effusion PEx
- Dullness to percussion
- Decreased or absent tactile
fremitus - Decreased breath sounds
- No voice transmission
What is the best CXR view for pleural effusion?
CXR in lateral decubitus view
- can detect as little as 50cc of fluid
- more sensitive
CXR findings
- Blunt costophrenic angle
2. Meniscus laterally
What is more sensitive than CXR in diagnosing a pleural effusion?
CT chest
- Detect as little as 2-10cc fluid
- Distinguish pleural thickening from fluid
When would you consider a CT angiogram?
Rule out PE
What do we use Lights criteria for?
differentiate between transudative fluid vs. exudative fluid
How sensitive is cytology analysis of pleural fluid?
60%
Look for malignancy this way
Indications for thoracentesis
- Newly detected pleural effusion- for diagnostic purposes
- Therapeutic sx relief
- Imaging suggest complicated effusion (located)
- Empyema
- Atypical features of CHF
When is a thoracentesis contraindicated?
Small volume fluids= <1 cm thickness on a lateral decubitus film
What is one of the main complication of a thoracentesis?
Pneumothorax
Transudative effusions
Result from systemic imbalances in hydrostatic
and oncotic forces
Causes for Transudative effusions
- Heart Failure
- Nephrotic syndrome
- Hepatic hydrothorax
Exudative effusions
Pleural capillary permeability ↑ leading to elevated protein/cellular content
Causes for Exudative effusions
- Malignancy
- Infectious
- PE
- Postcardiac injury
Chylothorax
Build up up cholesterol
long term management of pleural effusion
- PRN thoracentesis
- PleurX catheter- Refactory effusions
- Pleurodesis: Surgical and Chemical (Talc, Bleomycin)
Pneumothorax
- Presence of air or gas in the pleural cavity
- Usually spontaneous
Primary Spontaneous Pneumothorax (PSP)
Occurs without a precipitating event in a person without known lung disease
Secondary Spontaneous Pneumothorax (SSP)
Occurs as complication of an underlying lung disease
What is the #1 cause for Pneumothorax?
Smoking= 91%
What is the most common population of a spontaneous Pneumothorax?
Tall, thin, young men from age 20-40
Spontaneous Pneumothorax clinical presentation
Sudden onset of dyspnea (80%) and pleuritic CP (90%)***
Indication for CT chest in a Spontaneous Pneumothorax
- Differentiate pneumothorax from large subpleural bullae
- Evaluate for underlying lung pathology
3.
What indicates a Spontaneous Pneumothorax on an US?
Absence of “sliding lung sign”
Define what a small pneumothorax is and treatment
< or equal to 2-3 cm= Observe
Define what a large pneumothorax is and treatment?
> 3 cm
Needle aspiration
Indication for chest tube
- No response to needle aspiration
- Secondary spontaneous pneumothorax (SSP)
- Recurrent PSP
- Hemothorax
What is a Video Assisted Thoracoscopy? (VATS)
Pleurodesis by:
- Pleural abrasion
- Partial pleurectomy
Indications for VATS
- Persistent air leakr
- Recurrence
- Chest tube required on first occurrence
- Job where recurrence could be harmful to others (ie. Pilot), 4. bleb/bullae resection (COPD pt)
Secondary Spontaneous Pneumothorax treatment
- Hospitalized
2. Chest tube> Thoracentesis
Tension Pneumothorax clinical presentation
- Worsening dyspnea
- Hypotension
- Diminished BS
- Distended neck veins
- Tracheal deviation
Tension Pneumothorax Treatment
IMMEDIATE decompression
Chest tube
Tension Pneumothorax CXR findings
- Mediastinal shift and tracheal
deviation to contralateral side - Ipsilateral flattening or
inversion of diaphragm
Hallmark clinical presentation of acute respiratory distress
- Bilateral radiographic opacities
- Hypoxemia
- Significant SOB 6-72 hrs after inciting event
Hallmark pathologic findings acute respiratory distress
Diffuse alveolar damage
CXR findings in acute respiratory distress
- Diffuse or patchy B/L infiltrates
2. Usu. spare the costophrenic angles
Acute respiratory distress diagnostics
ABG:
- Hypoxemia
- acute respiratory alkalosis
- PaO2/FiO2 < 300 mm Hg
- Increased alveolar-arterial oxygen (A-a) gradient
Acute respiratory distress treatment
- Intubation
- Mechanical ventilation
- Prone positioning in bed
- DVT and GI prophylaxis
* HIGH MORTALITY