Plasmodium Flashcards

1
Q

Especies patógenas de plasmodium

A

Vivax, ovale, malariae, falciparum

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2
Q

Especie mas patogena para el ser humano

A

Falciparum

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3
Q

vector de la enfermedad

A

anopheles

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4
Q

Forma infectante del plasmodium

A

esporozoitos

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5
Q

Forma asexual e infectante del plasmodium

A

merozoitos

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6
Q

1er organo que invaden al entrar en torrente sanguineo

A

Higado (en <1 hra)(fase exoeritrocitica)

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7
Q

forma durmiente que provoca las recurrencias

A

hipnozoitos

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8
Q

periodo de incubacion

A

10-15 dias

*excepto malariae; hasta 28 dias

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9
Q

Estudio dx de primera eleccion

A

frotis de gota gruesa

*PCR o ELISA en caso de que sea negativa

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10
Q

Tx de 1ra eleccion

A

Cloroquina

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11
Q

Farmaco usado en la profilaxis cuando viajan a zonas endemicas

A

Mefloquina

*NOM cloroquina

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12
Q

Farmaco contraindicado en DG6P

A

Primaquina

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13
Q

Farmaco que requiere monitarizacion cardiaca

A

Quinidina

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14
Q

Farmaco indicado en Falciparum resistente a cloroquina sin complicaciones severas

A

1- Artemeter-lumefrantina (VO)

2- Atovacuona-proguanilo (VO)

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15
Q

Farmaco indicado en Falciparum resistente a cloroquina con complicaciones severas

A

1- Artesunato o quinina (IV)

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16
Q

Farmaco usado en caso de recurrencia (por su actividad frente a hipnozoitos)

A

Primaquina