Placentation Flashcards

1
Q

What are the 3 phases of placental development?

A
  1. Chorionic (histotrophic)
  2. Choriovitelline (histotrophic)
  3. Chorioallantoic (mostly hematrophic)
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2
Q

What are areolae and in which species are they found?

A

Areas of transfer in chorioallantoic placenta over areas of uterine glands; found in all non-deciduate species

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3
Q

Which species have deciduate placenta (i.e. have uterine bleeding normally at parturition)? Which cell types are involved in invasion?

A

Carnivores
Rodents
Higher primates

Syncytiotrophoblasts - invade uterus (as well as cytotrophoblasts)

Decidual cells - maternal, immunological role

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4
Q

Which species have diffuse placenta?

A

Horse, pig

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5
Q

Which species have cotyledonary placenta?

A

Ruminants

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6
Q

Which species have zonary placenta?

A

Carnivores (dog, cat, ferret)
- Ferret/raccoon = double

Rings are sites of hem atrophic exchange; where syncytiotrophoblasts form

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7
Q

Which species have discoid placenta?

A

Higher primates

Rodents

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8
Q

Which species have epitheliochorial placenta?

A

Pig, horse

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9
Q

Which species have synepitheliochorial placenta? Which cell types are found there, and what do they produce?

A

Ruminants

Binucleate cells - make lactogen - similar to growth hormone

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10
Q

Which species have endotheliochorial placenta?

A

Carnivores

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11
Q

What is the difference between the chorioamnion and the amniochorion?

A

Amniochorion - pig (and human) only - vascularized courtesy of allantois

Chorioamnion - cows and all other animals - no vascularization

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12
Q

Which species have hemochorial placenta?

A

Higher primates

Rodents

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13
Q

What is the dominant protein in the uterine milk of pigs, and what does it do?

A

Uteroferrin; transfers iron for development of fetal RBCs

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14
Q

Where is the trilaminar omphalopleure and in which species is it clinically important?

A

Where yolk sac meets chorion; horses

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15
Q

Which areas lack micro cotyledons in the horse?

A
  1. Oviducts

2. Cervical star (end of the uterine body)

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16
Q

Which species has endometrial cups? Where are they located? When do they develop? What is their function?

A
  1. Horse
  2. Chorion b/t allantois and yolk sac (“chorionic girdle”)
  3. 35-125 days
  4. Trophoblasts (that invade uterine eptitheliujm) secrete equine chorionic gonadotrpin (induce luteiniation of follicles to make progesterone, which stimulates production of uterine milk)
17
Q

How does the shape of placentomes differ between ruminants?

A

Cow - convex

Small ruminants - concave

18
Q

What cannot pass through the placenta, and what can?

A

Cannot pass: macromolecules and maternal hormones

Can pass: viruses, toxins, parasites