Placenta Flashcards
3 major functions of placenta
organ of exchange, produces hormones (progesterone, hCG, somatomammotropin), immunological barrier
Hemochorial
maternal blood comes in direct contact with the chorion
Fetal component of placenta
villous chorion (chorionic villi)
Maternal component of placenta
decidua basalis (deep to conceptus)
Umbilical cord structure
2 umbilical arteries, 1 umbilical vein, Wharton’s jelly (mucous connective tissue)
decidua capsularis
decidua lying directly over the conceptus
decidua perietalis
decidua not below or above conceptus
Cotyledons
small compartments on maternal side of placenta
Components of villous chorion
Trophoblast and extra embryonic mesoderm
Functions of cytotrophoblast shell
- Firmly attaches the chorion to the endometrium
- Perforated by maternal vessels to supply and drain blood from intervillous spaces
- Degenerates by term and is replaced by fibrinoid material
Stem (anchoring) villi
extend from the chorionic plate to the decidua basalis
Terminal villi
branch from the side of anchoring villi and represent sites where the nutrient and gas exchange will occur between maternal and fetal blood
Initially (by month 4), the outer surface of the terminal villi form a placental membrane that consists of 4 layers:
Syncytiotrophoblast
Cytotrophoblast
Extraembryonic mesoderm
Fetal endothelium
By the beginning of month 4, the cytotrophoblast degenerates, leaving only 2 layers in the placental membrane:
Syncytiotrophoblast
Fetal endothelium
Chorionic frondosum
Villi proliferate on the embryonic pole