Placenta Flashcards

1
Q

The foetal and maternal circulations do not ,ix. T/F?

A

True

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2
Q

What is the name of the series of lobes into which the basal plate of the placenta is divided?

A

Cotyledons

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3
Q

What is the name of the maternal part of the placenta?

A

Basal plate

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4
Q

Dichorionic diamniotic twinning results from twinning which occurs between….?

A

Days 1-3

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5
Q

Monochorionic diamniotic twinning results from twinning which occurs between….?

A

Fays 4-8

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6
Q

Monochorionic monoamniotic twinning results from twinning which occurs between….?

A

Days 8-13

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7
Q

Conjoined twins results from twinning which occurred between days…?

A

13 and 15

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8
Q

Which layer of the embryonic part of the placenta proliferates and which layer is non-dividing?

A

Cytotrophpblast layer proliferates

Syncitiotrophoblast layer is non Dividing

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9
Q

Within which trophoblast layer do lacunae begin to form after day 8 of conception?

A

Syncitiotrophoblast

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10
Q

The lacunae of the syncitiotrophoblasts are the precursors of…?

A

Intervillous space

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11
Q

Towards the end if the second week small projections of the cytotrophoblast layer begin to expand into the syncitiotrophoblast. What do these form?

A

Primary chorionic villi

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12
Q

Extraembryonic mesoderm grows into the primary chorionic villi to form…?

A

Secondary chorionic villi

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13
Q

What happens to secondary chorionic villi to convert them to tertiary chorionic villi?

A

Small embryonic blood vessels start to grow into the villi

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14
Q

What is the function of the intervillous space of the placenta?

A

It is the site if exchange between foetal and maternal blood

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15
Q

The stroma is the villous core. What cells is it mainly composed of?

A

Fibroblast cells

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16
Q

The villous cytotrophoblast layer is only present in early pregnancy. T/F?

A

True

17
Q

How many main stem villi are contained within the placenta?

A

60-70

18
Q

At term, what is the only layer of the placenta which separates the endothelium of the villous capillaries from the maternal circulation?

A

Syncitiotrophoblasy

19
Q

The spiral arteries are remodelled from low flow high resistance to high flow low resistance during development of the placenta. T/F?

A

True

20
Q

Which vessel(s) carries deoxygeneated blood from the foetus?

A

Umbilical arteries

21
Q

Which vessel(s) carries oxygenated blood to the foetus fo the placenta?

A

Umbilical vein

22
Q

What vessels transport maternal blood to and from the placenta?

A

Uterine arteries supply placenta with oxygenated blood

Uterine veins drain deoxygenated blood from the placenta

23
Q

What substances diffuse or are transported from maternal to foetal blood?

A
Oxygen
Glucose
Fatty acids
Ionic substances
Antibodies
24
Q

In the placenta, glucose undergoes facilitated diffusion via which transporter to reaCh the foetal blood?

A

Hexose transporter

25
Q

What is the barker hypothesis?

A

The hypothesis which states that babies which are too small at borth are predisposed to adult diseases

26
Q

Preecmapsia is a disorder of late pregnancy. What blood pressure and level of proteinuria are diagnostic of preeeclampsia?

A

Bp over 140/90 mmHg

Proteinuria over 300mg in 24hours

27
Q

What happens to cause preeclampsia?

A

There is invasion of trophoblasts into the maternal tissue and the spinal arteries do not undergo physiological change and blood flow to the placenta is reduced

28
Q

What adult conditions are linked to low birth weight?

A

Obesity

Cardiovascular disease