Placenta Flashcards
The foetal and maternal circulations do not ,ix. T/F?
True
What is the name of the series of lobes into which the basal plate of the placenta is divided?
Cotyledons
What is the name of the maternal part of the placenta?
Basal plate
Dichorionic diamniotic twinning results from twinning which occurs between….?
Days 1-3
Monochorionic diamniotic twinning results from twinning which occurs between….?
Fays 4-8
Monochorionic monoamniotic twinning results from twinning which occurs between….?
Days 8-13
Conjoined twins results from twinning which occurred between days…?
13 and 15
Which layer of the embryonic part of the placenta proliferates and which layer is non-dividing?
Cytotrophpblast layer proliferates
Syncitiotrophoblast layer is non Dividing
Within which trophoblast layer do lacunae begin to form after day 8 of conception?
Syncitiotrophoblast
The lacunae of the syncitiotrophoblasts are the precursors of…?
Intervillous space
Towards the end if the second week small projections of the cytotrophoblast layer begin to expand into the syncitiotrophoblast. What do these form?
Primary chorionic villi
Extraembryonic mesoderm grows into the primary chorionic villi to form…?
Secondary chorionic villi
What happens to secondary chorionic villi to convert them to tertiary chorionic villi?
Small embryonic blood vessels start to grow into the villi
What is the function of the intervillous space of the placenta?
It is the site if exchange between foetal and maternal blood
The stroma is the villous core. What cells is it mainly composed of?
Fibroblast cells
The villous cytotrophoblast layer is only present in early pregnancy. T/F?
True
How many main stem villi are contained within the placenta?
60-70
At term, what is the only layer of the placenta which separates the endothelium of the villous capillaries from the maternal circulation?
Syncitiotrophoblasy
The spiral arteries are remodelled from low flow high resistance to high flow low resistance during development of the placenta. T/F?
True
Which vessel(s) carries deoxygeneated blood from the foetus?
Umbilical arteries
Which vessel(s) carries oxygenated blood to the foetus fo the placenta?
Umbilical vein
What vessels transport maternal blood to and from the placenta?
Uterine arteries supply placenta with oxygenated blood
Uterine veins drain deoxygenated blood from the placenta
What substances diffuse or are transported from maternal to foetal blood?
Oxygen Glucose Fatty acids Ionic substances Antibodies
In the placenta, glucose undergoes facilitated diffusion via which transporter to reaCh the foetal blood?
Hexose transporter
What is the barker hypothesis?
The hypothesis which states that babies which are too small at borth are predisposed to adult diseases
Preecmapsia is a disorder of late pregnancy. What blood pressure and level of proteinuria are diagnostic of preeeclampsia?
Bp over 140/90 mmHg
Proteinuria over 300mg in 24hours
What happens to cause preeclampsia?
There is invasion of trophoblasts into the maternal tissue and the spinal arteries do not undergo physiological change and blood flow to the placenta is reduced
What adult conditions are linked to low birth weight?
Obesity
Cardiovascular disease