PL 7, 8, 9 (PL 7)

Question 1

what is molecular recognition

Answer 1

• the way in which molecules interact in terms of intermolecular and non-covalent bonds

Question 2

define pharmacophore

Answer 2

the part of the molecule that gives the medicine its pharmacological effect

Question 3

describe the features of a pharmacophore

Answer 3

• can be modified by changing its functional group to make the medicine more effective or reduce side effects
• interacts with receptor sites through weak interactions
• fit into receptor sites with correct size, shape and orientation with which they can form weak bonds