Pituitary Drugs

Question 1

Classification of Pituitary drugs

Answer 1

• VARIETY OF DRUGS AFFECT THE PITUITARY GLAND
• THEY AUGMENT OR ANTAGONIZE THE NATURAL EFFECTS OF THE PITUITARY HORMONES
• TABLE 13-1 – ANTERIOR AND POSTERIOR PITUITARY HORMONES, FUNCTION AND MIMICKING
DRUGS

Question 2

Octreotide Classification

Answer 2

SOMATOSTATIN (GH INHIBITOR ANALOGUE)

Question 3

DESMOPRESSIN CLASSIFICATION

Answer 3

SYNTHETIC ADH

Question 4

MOVEMENT OF OCTREOTIDE

Answer 4

VARIES DEPENDING ON ROUTE; SHORT ½ LIFE NECESSITATING FREQUENT ADMINISTRATION

Question 5

MOVEMENT OF DESMOPRESSIN

Answer 5

VARIES DEPENDING ON ROUTE

Question 6

ACTION OF OCTREOTIDE

Answer 6

ANTAGONIZES THE EFFECTS OF NATURAL GH – INHIBITS GH RELEASE

Question 7

ACTION OF DESMOPRESSIN

Answer 7

MIMIC THE EFFECTS OF NATURALLY OCCURRING ADH – INCREASING THE WATER ABSORPTION IN THE DISTAL TUBULES AND COLLECTING DUCTS OF THE KIDNEY – CONCENTRATE URINE – DECREASE WATER EXCRETION BY UP TO 90%

Question 8

NURSING CONSIDERATIONS FOR OCTREOTIDE (ADVERSE AFFECTS)

Answer 8

FATIGUE, MALAISE, HYPO/HYPER- GLYCEMIA, D/N/V, DYSPNEA, ARTHRALGIA, CVS CONDUCTION ABNORMALITIES

Question 9

NURSING CONSIDERATIONS FOR DESMOPRESSIN (ADVERSE AFFECTS)

Answer 9

HTN, FEVER, VERTIGO, HEADACHES, NAUSEA, HEARTBURN, GI/UTERINE CRAMPING, NASAL IRRITATION/CONGESTION, TREMOR, SWEATING

Question 10

OCTREOTIDE INDICATIONS

Answer 10

TREATMENT OF ACROMEGALY; (ALSO TREATMENT FOR CARCINOID TUMORS AND TREATMENT OF ESOPHAGEAL VARICES)

Question 11

DESMOPRESSIN INDICATIONS

Answer 11

DIABETES INSIPIDUS (PREVENT/ CONTROL POLYDIPSIA AND POLYURIA AND
DEHYDRATION); (ALSO USEFUL FOR TYPES OF HEMOPHILIA D/T EFFECTS ON CERTAIN
COAGULATION FACTORS)

Question 12

OCTREOTIDE ADMINISTRATION

Answer 12

IV/SC/DEPOT IM

Question 13

DESMOPRESSIN ADMINISTRATION

Answer 13

PO/SL/IV/IM/SC/INTRANASAL