Pioglitazone Flashcards
1
Q
Moa
A
• Increases insulin sensitivity
• activates PPARy
2
Q
ADRs
A
• bone fractures
• weight gain
• numbness
• odema
3
Q
What drugs class does this drug belong to?
A
Thiazolidineiones
• pioglitazone
• rosiglitazone
4
Q
Pros and cons
A
Pros
• little hypo risk
• good HbA1c reduction
Cons
• bladder cancer
• odema
• fractures
• risk of CVD
• weight gain