Pioglitazone Flashcards

1
Q

Moa

A

• Increases insulin sensitivity
• activates PPARy

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2
Q

ADRs

A

• bone fractures
• weight gain
• numbness
• odema

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3
Q

What drugs class does this drug belong to?

A

Thiazolidineiones
• pioglitazone
• rosiglitazone

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4
Q

Pros and cons

A

Pros
• little hypo risk
• good HbA1c reduction

Cons
• bladder cancer
• odema
• fractures
• risk of CVD
• weight gain

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