Moa?
Inhibits influx of Ca though the L type channel in the smooth peripheral muscle and myocardium
• reducing heart contracility
• vasodilation
• inhibiting electrical signals
• antiarrythmic
more cardio selective
ADRs
• constipation
• headache
• flushes
• peripheral odema
• tachycardia
Examples
Verapamil
Diltiazam