Fibric Acid Derivatives Flashcards
1
Q
Moa
A
• increase HDL
• activate PPAR - increasing lipolysis
2
Q
ADRS?
A
•GI disturbance: flactulane, abdominal pain, N&V
• myopathy, myosis
3
Q
CI
A
• pregnancy
• breastfeeding
• active liver disease (pancreatitis)
• gall bladder
4
Q
Monitor
A
Hepatic function, after every 3 months
5
Q
Examples.
A
• fenofibrates
• gemfibrozil
6
Q
Indication
A
Lipid disorders