Pigment Disorders

Question 1

What is Melasma?
Where is it m/c located?
Are M or F affected more?

Answer 1

• Chronic recurring disorder of hyperpigmentation d/t excessive melanin deposition
• Symmetrical (face, cheeks, upper lip, forehead)
• F > M

Question 2

Contributing factors of Melasma?

Answer 2

• Genetics
• Sun/UV exposure
• Hormones/Pregnancy
• Photosensitizing meds & Anticonvulsants

Question 3

What is Vitiligo?
What’s it associated with?

Answer 3

• Chronic dis-pigmentation disorder that results in white spots d/t loss of melanocytes
• Associated with AI conditions like Hashimotos

Question 3

How do you treat Melasma?

Answer 3

COSMETIC
- Avoid sun
- Hydroquinone cream-bleaching agent
- Chemical peel like Glycolic Acid

Question 4

How do you treat Vitiligo?

Answer 4

• Stabilization therapy like oral steroids, IM steroids +/-NBUVB (targeted light therapy)
• 1st line for <10%TBSA = mid-high potency topical steroids (pulse therapy is recommended)