PID Flashcards
In younger women the cervical squamous epithelium is
less pronounced, more columnar epithelium
3 ways in which initial infectious agents ascend into uterus and tubes
1- cell to cell mediated
2- tubal transport
3- adhesion molecules
Pathogenesis of PID
1- epithelial cell degeneration and deciliation along fallopian tube submucosal inflammator infiltrate
2- edema of the tube augments the intraluminal agglutination –> endosalpingitis
Clinical presentation of PID
1- lower abdominal pain/may be subtle 2- abnormal discharge 3- dyspareunia 4- dysuria 5- N/V - RAREly right upper quadrant pain
What are lab tests that are NOT specific for PID
- CBC, differential and ESR/C-RP - helpful for TOA
what finding is low in culture positive PID
Fever! only 3% present as such
Diagnostic criteria minimum
1- Lower abdominal tenderness
2- Adnexal tenderness
3- cervical motion tenderness
Complications of PID
Tubo-ovarian abscess Pelvic abcess adhesions throughout pelvis Chronic pain Infertility increases 10 fold Ectopic pregnancy
Outpatient antibiotic regimens should include
1- Ceftriaxone and Dox -/Metronidazole
2- Ofloxacin and metronidazole (FQ resistance
3. Levofloxacin and metronidazole
Inpatient Abx
1- IV Cephalosporin and Dox
2- Clindamycin IV + Gentamicin
3- Ofloxacin IV and Metro IV
Dox is for
Chalmydia
2 cephalosporins IV for inpatients
Cefoxitin and Cefotetan