fetal complications Flashcards
Hydrops is
an abnormal accumulation of fluid in MORE THAN 1 body cavity
causes of Hydrops
Immune (10-15%) - alloimmunization with Anti-D aB
Non-Immune causes
Hydrops can present as
increased systolic flow in MCA
ABO, lewis antibodies are most common but they do NOT cause
Fetal anemia
which type of antibodies in the Rh system cause the majority of cases of obstetric complications?
Anti-D antibodies
Under what 2 circumstances can a woman become allo-immunized?
1- blood transfusion
2- pregnancy
when do Ab cross the placenta in a second pregnancy?
~ 17-18 weeks
what are the 4 risks for Rh+ fetus?
fetal anemia Hydrops IUFD newborn anemia severe jaundice
Indirect Coomb’s test
Patient serum incubated with known RBC antigens
The HIGHER the titer
Greater risk of Rh positive fetus
elevated peak systolic velocity means
Fetal anemia! BEFORE hydrops
if you confirm fetal anemia
can do an U/S guided transfusion
rhogam is given routinely at 28 weeks UNLESS
FATher is Rh negative as well as mother
if non-immune hydrops - baby losing blood think
TTTS
if non-immune hydrops and baby is hemolysing
- parvovirus/slapped cheek or fifth disease