Physiology: Rate of gas exchange across alveolar membrane Flashcards

1
Q

what are the 4 factors that influence the rate of gas exchange across the alveolar membrane

A

partial pressure gradient of O2 and CO2
diffusion coeffecient for O2 and CO2
surface area of alveolar membrane
thickness of alveolar membrane

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2
Q

what is Daltons Law of partial pressures

A

The total pressure exerted by a gaseous mixture = the sum of the partial pressures of each individual component in the gas mixture

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3
Q

what does partial pressure of a gas determine

A

the pressure gradient for that gas

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4
Q

what is the partial pressure of a gas

A

the pressure that one gas in a mixture of gases would exert if it were the only gas in the whole volume occupied by the mixture
(at constant temp.)

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5
Q

describe how gases move by partial pressure gradient

A

they move from higher partial pressure to lower partial pressure

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6
Q

what is the diffusion coefficient of a gas

A

the solubility of that gas in membranes

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7
Q

why is the partial pressure gradient for CO2 much smaller than that for O2

A

because CO2 is more soluble(20 times) in membrane than O2

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8
Q

what is Ficks law of diffusion

A

amount of gas that moves across a membrane in unit time is proportional to the area of tissue BUT inversely proportional to its thickness

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9
Q

describe the factors that would increase rate of gas transfer(4)

A

increase surface area
decrease membrane thickness
increase diffusion coefficient
increase partial pressures

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