Physiology - Part 1 Flashcards

1
Q

what are the four functions of the respiratory system?

A

gas exchange
acid base balance
protection from infection
communication via speech

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2
Q

on average, how much oxygen is consumed per minute?

A

250ml

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3
Q

on average, how much carbon dioxide is produced per minute?

A

200ml

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4
Q

which structures constitute the upper respiratory tract?

A

mouth
nasal cavity
pharynx
larynx

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5
Q

which structures constitute the lower respiratory tract?

A

trachea
bronchi
bronchioles
alveoli

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6
Q

what maintains the patency of the airways in the trachea and bronchi?

A

C shaped rings of cartilage

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7
Q

what type of epithelium lines the respiratory tract?

A

pseudostratified ciliated columnar

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8
Q

which are more abundant - type I or type II pneumocytes?

A

type I

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9
Q

what are type I pneumocytes responsible for?

A

gas exchange

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10
Q

what are type II pneumocytes responsible for?

A

producing surfactant

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11
Q

what does boyle’s law state?

A

that the pressure exerted by a gas is inversely proportional to its volume (P proportional to 1/V)

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12
Q

what does dalton’s law state?

A

the total pressure of a gas mixture is the sum of the pressures of the individual gases

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13
Q

what does charles law state?

A

the volume occupied by a gas is directly related to the absolute temperature

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14
Q

what does henry’s law state?

A

the amount of gas dissolved in a liquid is determined by the pressure of the gas and its solubility in the liquid

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15
Q

is intrapleural pressure positive or negative?

A

negative

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16
Q

which muscles are used for inspiration?

A

external intercostals
diaphragm
sternocleidomastoids
scalenes

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17
Q

which muscles are used for expiration during high respiratory load?

A

internal intercostals and abdominal muscles

18
Q

which muscles are used for expiration at rest?

A

expiration is passive at rest

19
Q

what is the tidal volume?

A

the volume of air breathed in or out of the lungs with each breath

20
Q

what is the expiratory reserve volume?

A

the maximum volume of air which can be expelled from the lungs at the end of a normal expiration

21
Q

what is the inspiratory reserve volume?

A

the maximum volume of air which can be drawn into the lungs at the end of a normal inspiration

22
Q

what is the residual volume?

A

the volume of gas in the lungs at the end of a maximal expiration

23
Q

which components make up the vital capacity?

A

tidal volume + inspiratory reserve volume + expiratory reserve volume

24
Q

which components make up the total lung capacity?

A

vital capacity (tidal volume + inspiratory reserve volume + expiratory reserve volume) + residual volume

25
which components make up the inspiratory capacity?
tidal volume + inspiratory reserve volume
26
which components make up the functional residual capacity?
expiratory reserve volume + residual volume
27
what does FEV1 mean?
forced expired volume in 1 second
28
what does FEV1:FVC mean?
the fraction of forced vital capacity expired in 1 second
29
what is pulmonary (minute) ventilation?
total air movement into / out of the lungs
30
what is alveolar ventilation?
fresh air getting to alveoli and therefore available for gas exchange
31
what is the alveolar partial pressure of O2 during normal ventilation?
100 mmHg / 13.3 kPa
32
what is the alveolar partial pressure of CO2 during normal ventilation?
40 mmHg / 5.3 kPa
33
is surfactant more effective in smaller alveoli or larger alveoli?
smaller alveoli - it's more concentrated
34
what is the name of the syndrome newborns suffer when they don't produce enough surfactant?
Infant Respiratory Distress Syndrome (IRDS)
35
when there is a large increase in lung volume for a small increase in intrapleural pressure, does this correlate to hgih or low compliance of the lungs?
high compliance
36
with low compliance, is there a small or a large increase in lung volume when there's a large increase in intrapleural pressure?
small
37
what is the difference between obstructive and restrictive lung disease?
obstructive is obstruction of air flow especially on expiration restrictive is restriction of lung expansion
38
what is a normal FEV1/FVC ratio?
80%
39
how does the spirometry graph of someone with an obstructive lung disease compare to the normal one?
shallower and longer
40
how does the spirometry graph of someone with an restrictive lung disease compare to the normal one?
shallower and shorter
41
what does a low FEV1/FVC ratio indicate?
obstructive lung disease
42
what does a high FEV1/FVC ratio indicate?
restrictive lung disease