Physiology Flashcards
body fluid compartments
intracellular fluid (ICF) extracellular fluid (ECF)
extracellular fluid compartments
interstitial fluid
blood plasma
extracellular fluid volume
1/3 total body volume
20% body weight
intracellular fluid volume
2/3 total body volume
40%
total body water volume
60% body weight
ICF - 40%
ECF - 20%
in terms of body percentages, males have more what, while females have more what?
males - water
females - fat
what charge are proteins usually
negative
what would happen if the liver stopped producing proteins
the protein concentration level in the blood would drop, causing water to leave the capillaries into the interstitial fluid which causes edema
What do Starling forces do?
substances moving between plasma and interstitial fluid must cross the capillary wall
what is osmosis
movement of water to a higher concentration so that it reaches the equilibrium point
what happens to a cell is an isotonic environment
no change
the cell is the same concentration as the extracellular fluid, so there would be no net movement of water
what happens to a cell in a hypotonic environment
water would move into the cell from the extracellular fluid
cell swells and can potentially burst
what happens to a cell in a hypertonic environment
water moves out of cell into the extracellular fluid
cell shrinks/ crenates
how does the body know if the blood is too concentrated
there are osmoreceptors in the hypothalamus
what concentrations are higher outside the cell
oxygen
sodium
calcium
what concentrations are higher inside the cell
carbon dioxide
potassium
cytosol function
metabolism, protein synthesis
cytoskeleton function
cell shap and movement
intracellular transport
nucleus function
genome
dna and rna synthesis
mitochondria function
atp synthesis
calcium storage
smooth er function
synthesis of lipids, calcium storage
free ribosomes function
translation of mrna to cytosolic proteins
rough er function
translating mrna into membrane associated proteins or for secretion out of cell
lysosome function
intracellular degradation
endosome function
cellular uptake of cholesterol
removal of receptors from membrane
internalization of large particles such as bacti
golgi apparatus
modification sorting and packaging of proteins and lipids for delivery to other organelles within cell or for secretion
proteosome function
degradation of intracellular proteins
peroxisome
detoxification of substances
what factors affect the rate of diffusion?
lipid solubility (direct) molecular size (inverse) concentration gradient (direct) membrane surface area composition of lipid later
ficks law of diffusion
rate of diffusion is directly proportional to surface area, concentration gradient and membrane permeability
what is membrane permeability relied upon
membrane permeability is directly proportional to lipid solubility and inversely proportional to molecular size