Physiology Flashcards

1
Q

What are the three types of muscle in the body?

A

Skeletal

Cardiac

smooth

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2
Q

What produces the light and dark striations in skeletal and cardiac muscle?

A

Myosin produces dark

Actin produces light bands

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3
Q

What is a motor unit?

A

A single alpha motor neuron and all the skeletal muscle fibres it innervates

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4
Q

From big to small what are the names of the muscles?

A

Whole muscle

Muscle fibre

Myofibirl

Sarcomere

Myocin

Actin

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5
Q

What is the nerurotransmitter at the neuromuscular junction

A

Acetlycholine

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6
Q

How is an action potential stimulated in skeletal muscle?

A

Action potential spreades down T-tubules triggering calcium ion release from the lateral sacs of the sarcoplasmic reticulum

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7
Q

What is the functional unit of a muscle called?

A

A Sarcomere

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8
Q

What is a functional unit ?

A

The smallest component of an organ which is capable of performing all the functions of that organ

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9
Q

What are the 4 sarcomere zones

A

IAHM

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10
Q

What is the I zone?

A

Actin filamints that don’t overlap with myosin

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11
Q

What is the A band?

A

Area where Actin and Myosin filaments overlap

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12
Q

What is the H zone?

A

Lighter area in the middle where actin filaments dont reach

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13
Q

What is the m line?

A

Vertical band straight down the middle of the A and H zones

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14
Q

What is responsible for muscle tensions

A

Actin filaments sliding on myocin filaments

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15
Q

For what is ATP needed for in muscles?

A

During muscle contraction to power contraction

During relaxation to release cross bridges

and to pump calcium back into the sarcoplasmic reticulum

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16
Q

How does the skeletal muscle twitch compare to the action potential?

A

The action potential is much shorter so you can fire a bunch of action potentials in order to produce a stronger twitch

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17
Q

What cant Cardiac muscle be tetanised?

A

Because of the refractory period

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18
Q

What are the three metabolic pathwapys that supply ATP in muscle fibres?

A

Transfer of high energy phosphate from creatine phosphate to ADP

Oxidative phosphorylation

Glycolysis

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19
Q

What is the main source of ATP when O2 is present?

A

Oxidative phosphorylation

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20
Q

What is the main source of ATP when O2 is not present ?

A

Glycolysis

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21
Q

What are the three types of skeletal muscle fibres?

A

Slow-oxidative

Fast-oxidative

Fast-glycolytic

22
Q

What spinal segment and peripheral nerve is tested during the knee jerk?

A

L3 and L4

Femoral Nerve

23
Q

What are muscle spindles?

A

Intrafusal fibres with annulospiral fibres which sense when the muscle is stretched

24
Q

What are the three types of joints?

A

Synovial

Fibrous

Cartilaginous

25
What do all synovial joints have which cartilaginous joints dont?
A synovial membane
26
What does the synovial fluid do for the chondrocytes?
Supply it with oxygen and nutrients
27
What gives synovial fluid its high viscosity?
hyaluronic acid
28
What type of cartilage makes up most of the articular cartilage?
Hyaline
29
Where does articular cartilage get its nutrients from?
Recives nutrients from synovial fluid It has no blood supply of its own.
30
What is special about the nucleus of skeletal muscle cells?
They have loads of nuclei per cell
31
What are muscle bundles called?
Fasicles
32
What are the layers of connective tissue which organises muscles?
Epimysium Perimysium Endomysium
33
What do you call cells found in the cartilage?
Chondrocytes
34
Where do chondrocytes live?
Lacuna
35
What do chondrocytes do?
Secrete and maintain the extracellular matrix around them
36
What makes up the extracellular matrix in hyaline cartilage
75% water 25% Organic material of which 60% is type II collagena nd 40% is proteoglycan aggregates
37
What does Hyaline cartilage look like?
Blue-white and translucent
38
What does Elastic cartilage look like?
light yellow
39
What are the three types of cartilage?
Hyaline cartilage Elastic cartilage Fibrocartilage
40
What is bone made up off?
Mostly minerals, collagen and water
41
What are the two types of bone you would find in a long bone?
Solid Cortical Bone Spongy Cancellous or trabecular bone
42
What are cement lines?
Lines found in osteons that have formed during remodelling
43
What does Cortical bone have that Trabeculae/Cancellous bone does not?
Cancellous/Trabecular bone does not have haversion cannals
44
What is located on bone surfaces and acts as a reserve pool of osteoblasts?
Osteoprogenitor cells
45
What are Osteoblasts?
Bone Builders B for builders
46
What is an osteocyte?
A bone cell trapped within the bone matrix
47
What do osteoclasts do?
Found on the surface of the bone, they are responsilbe for bone resorption. C for Cutters
48
How is mineral bone made ?
Osteoblasts secrete Osteoid which crystalises
49
What is the main mineral in bone?
Calcium Phosphate crystals
50
whats going on here?
Lamellar bone and woven bone undergoing remodelling