Pathology Flashcards
What are the main malignant bone tumours?
Osteosarcoma
Chondrosarcoma
Ewing’s sarcoma
What is a Chondrosarcoma?
Malignant tumour of bone composed of malignant chondrocytes
What is Maffucci’s syndrome?
Multiple enchondromatosis alongside Haemangiomas
How do you trat Chondrosarcomas?
Wide surgical excision
Limited use of chemo
Where do you usually find malignant tumours?
Ends of long bones
What is the usual clincial picture of a osteoid osteoma?
Dull pain which is worse at night
Relieved by NSAIDs
What is an Osteochondroma?
Cartilage capped bony projection which is continous with underlying bone
How do you treat a Chondroblastoma?
Biopsy and curettage plus liquid nitrogen
How do you treat an Osteosarcoma?
Biospy
Chemo
Surgery
Chemo
What is a Chordoma?
Very rare benign but locally invasive tumour arising from notocord remnants
What is this?
Osteoid Osteoma
What is a Haemangioma?
A dense collection of blood vessles
Who gets Chordomas?
Older adults
Who gets multiple myeloma?
Old people
What is essential for diagnosis of an Osteosarcoma?
Osteoid production
What is a giant cell tumour?
Bengin tumour arising from osteoclasts which makes cavaties in the medulla
What is this?
Osteosarcoma
What is this?
Ewing’s Sarcoma
What is the prognosis of an osteoid osteoma?
Will resolve without treatment in an average of 33 months
Who gets osteohondromas?
Young people
What is a Osteoid Osteoma?
Benign osteoblastic tumour
What is an Osteoblastoma?
Solitary, bengign self limiting tumour that produces osteoid and bone
What is a Chondroma?
Benign hyaline cartilage tumour arising from medullary cavity of bones of the hands and feet
how do you treat chordomas?
Chemotherapy
What is Ewing’s Sarcoma?
Highly malignant
Peripheral primitive neuroectodermal tumour
What is Multiple Myeloma?
Malignant proliferation of plasma cells in bone marrow
Often causes renal failure
What is Ollier’s Disease?
Rare developmental disorder resulting in Enchondromas forming unilateraly in one extremity
Not hereditary of familial
What primary malignant tumours commonly metastasize to bone?
Breast
Prostate
Lung
Renal
Thyroid
Ben percieves long red tibias
