Physiology 4.8 Flashcards
1
Q
When is synaptic density highest?
A
12-18 months after birth
2
Q
What is the relationship between vocabulary and cortical thickness?
A
significant negative correlation; thin
3
Q
What is the relationship between expressive and receptive language and cortical thickness?
A
positive correlation; thick
4
Q
Ohtahara Syndrome
A
- high voltage bursts and slow waves on EEG
- tonic spasms main seizures observed
- continuous
5
Q
Landau-Kleffner Syndrome
A
- epileptic aphasia
- extremely rare
- delayed development; loses ability to communicate
- personality and language disorders
- treatment: inhibit prunning
6
Q
Sever Myoclonic Epilepsy of infancy
A
- brief synchronous jerk of 1 or more limbs
- cortical epileptifrom discharge (generalized spike/sharp waves over motor cortex)
7
Q
Lennox-Gaustaut Syndrome
A
- multiple seizure types
- generalized pattern
- mental retardation, psychotic conditions
8
Q
Dravet Syndrome
A
- myoclonic epilepsy of infancy [severe form]
- SCN1A mutation
- fever/illness
- standard drugs do not work
9
Q
What is the most severe and the earliest-developing epileptic encephalopathy in children?
A
Ohtahara Syndrome
