Physiology 4.3 Flashcards

1
Q

What is being measured in intracellular recording?

A

potentials can be measured across the cell membrane

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2
Q

What is being measured in single unit extracellular recording?

A

potentials can be measured in the extracellular space relative to a common ground and close to a single neuron

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3
Q

What is being measured in field potentials?

A

potentials can be measured in the extracellular space relative to a common ground and not close to a single neuron; group of neurons

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4
Q

What is being measured in EEG?

A

potentials can be measured relative to a common ground from the scalp surface; very broad information

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5
Q

How does opening your eye affect an EEG?

A

dramatic change in electrical field; spike in EEG

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6
Q

How can the signal of an EEG be distorted or attenuated?

A

disturbance from tissue and bone

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7
Q

Why are there spatial and temporal limits of EEG recordings?

A

-signals are small

  • EEG is mainly a recording of cortical activity
  • *hippocampus, thalamus, brainstem do not contribute to EEG
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8
Q

How does the specificity of EEG compare to other intracellular recordings?

A
  • EEG measured in microvolts
  • intracellular measured in millivolts
  • *intracellular more specific
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9
Q

What does a large EEG signal represent?

A

amplitude is determined by synchronous firing

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10
Q

What is a normal EEG?

A

1-30 Hz
20-100 micro volts

alpha: 8-13 Hz
beta: 13-30 Hz
delta: 0.5-4 Hz
theta: 4-7 Hz

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11
Q

What are the alpha waves typical of, what is their amplitude, and where are they recorded?

A
  • typical of relaxed wakefulness
  • moderate amplitude
  • recorded over parietal and occipital lobules
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12
Q

What are the beta waves typical of, what is their amplitude, and where are they recorded?

A
  • typical of intense mental activity
  • lower amplitude
  • recorded over frontal areas
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13
Q

What happens when a relaxed subject is alerted?

A
  • EEG transitions from alpha to beta waves

- EEG desynchronizes

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14
Q

What are the theta and delta waves typical of?

A

-typical of drowsiness and early slow-wave sleep

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15
Q

What is the implication of theta or delta waves present during wakefulness?

A

sign of brain dysfunction

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16
Q

What is the implication of large, abrupt changes from baseline activity on an EEG?

A

synchronization of neuronal firing; paroxysmal activity

17
Q

How does a seizure focus appear on an EEG?

A

sharp spikes

18
Q

Which types of oscillations in the brain do drugs typically target to induce sleep?

A

thalamocortical oscillations

19
Q

What are additional ways to measure brain activity?

A

metabolic techniques
FMRI
PET
NIRS (near infared spectroscopy)