Physiology 4 Flashcards
What happens to O2 picked up by the blood at the lungs?
Transported in the blood to the tissues for use
What happens to CO2 produced at tissues?
Transported in the blood to the lungs for removal from the body
Henry’s Law
The amount of a given gas dissolved in a given type and volume of liquid at a constant temperature is proportional to the partial pressure of the gas in equilibrium with the liquid
What does Henry’s law mean?
- If the partial pressure in the gas phase is increased, the concentration of the gas in the liquid phase would increase proportionally
- The partial pressure of gas in solution is its partial pressure in the gas mixture with which it is in equilibrium
Resting O2 consumption of our body cells?
about 250ml/min
How many ml of O2 per litre of blood at a Po2 of 13.3kPa?
3ml 02
Under resting conditions how many ml of O2/ min is taken to tissues as dissolved O2?
Strenous activity?
15ml/min
90ml/min
In what 2 forms is O2 present in blood?
Bound to haemoglobin
Physically dissolved
What percent of 02 is bound to hameoglobin?
98.5%
What % of O2 is physically dissolved?
1.5%
Normal O2 concentration in arterial blood?
200ml/litre
What does each haemolglobin molecule contain?
4 haem groups which reversibly bind to 1 molecule of O2 each
Primary factor in determining the % saturation of haemoglobin with O2?
PO2
Oxygen Delivery Index Letters
DO2I
Oxygen Delivery Index Equation?
DO2I= CaO2 x Cl Do2I= Oxygen Delivery Index (ml/min/metre2) CaO2= Oxygen content of arterial blood (ml/L) CI= Cardiac Index (L/min/metre2)