Physiology Flashcards
Location of I cells
duodenum, jejunum
I cells secrete
CCK in response to FA and AA
Action of CCK
increase pancreatic secretion, GB contraction
relaxes sphincter of Oddi
decreases gastric emptying
Location of G cells
antrum of stomach
G cells secrete
gastrin in response to stomach distention/alkalinization, AA, peptides, vagal stimulation
Action of Gastrin
Increase H+, increase gastric mucosa and gastric motility
Zollinger-Ellison Syndrome
increases gastrin immensely
2 Amino acids the stimulate gastrin the most
Phenylalanine and Tryptophan
Location of K cells
Duodenum and Jejunum
K cells secrete
Glucose-dependent insulinotropic peptide
Exocrine action of Glucose-dependent insulinotropic peptide
decrease H+ in stomach
Endocrine action of Glucose-dependent insulinotropic peptide
Increase insulin release
Increase release from FA, AA, and ORAL glucose
Glucose-dependent insulinotropic peptide (GIP)
Produces migrating motor complexes
Motilin
Motilin receptor agonist
Erythomycin
Where motilin is secreted from
Small Intestine
Location of S cells
Duodenum
Secreted from S cells
Secretin
Action of Secretin
increase HCO3 from pancreas, decrease gastric acid secretion, increases bile secretion
Cause of Sercetin release
Increased acid and FA in lumen of duodenum
Location of D cell
Pancreatic Islets and GI mucosa
Secreted from D cells
Somatostatin, released in response to increased acid or decreased by vagal stimulation
Inhibits digestion and absorptionof substances needed for growth
Somatostatin