physiology Flashcards
What is pulmonary ventilation?
volume of air breathed in and out per minute
tidal volume X respiratory rate=?
pulmonary ventilation
What is physiology dead space?
anatomical dead space + alveolar dead space
What is anatomical dead space?
the parts of the bronchial tree not available for airway exchange
What is alveolar dead space?
ventilated alveoli which aren’t adequately perfused with blood
What does this supply?
A measure of effort that goes into stretching or distending the lungs?
pulmonary compliance
if less compliant then more work required= SOB
Which nerves cause bronchoconstriction?
parasympathetic
Which nerves cause bronchodilation?
sympathetic
What is forced expiratory volume in 1 second (FEV1)?
volume of air that can be expired in first second of expiration in an FVC determination.
What is the total ling capacity?
max volume of air the lungs can hold
What is vital capacity?
max volume of air that can be moved out during a single breath following a maximal inspiration
What is functional residual capacity?
volume of air left in the lungs at end of normal passive expiration
What is inspiratory capacity?
max volume of air inspired after quiet normal expiration
What is inspiratory reserve volume?
min volume of air left in lungs after a maximal expiration
What is expiratory reserve volume?
extra volume of air that can be maximally expired by max contraction beyond normal value of air after a resting tidal volume
What is tidal volume?
volume of air entering or leaving lungs during a single breath.
What are the muscles of active expiration?
abdominal muscles
internal intercostal muscles
What are the accessory muscles of inspiration?
sternocleidomastoid
scalenus
What are the major muscles of inspiration?
diaphragm
external intercostals
Name 3 things which keep the alveoli open
- surfactant
- alveolar interdependence
- transmural pressure gradient
Name 2 things which promote alveoli collapse
- surface tension
2. elastic connective tissue
What is alveolar interdependence?
when one alveoli starts to collapse, surrounding alveoli are stretched then recoil exerting expanding forces on the collapsing alevoli to open it.
What is respiratory distress syndrome?
when new born’s lungs cant make enough surfactant
What is pulmonary surfactant?
mix of lipids and proteins secreted by type 2 alveolar cells.
How does pulmonary surfactant work?
it intersperses between water molecules to reduce surface tension.
What is LaPlace’s Law?
P=2T/r
smaller alveoli have a higher tendency to collapse